Results 51 to 60 of about 2,509,838 (314)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Recordings of digital media life: Advancing (qualitative) media diaries as a method

open access: yesStudies in Communication Sciences, 2022
In times of digitalization, analyzing the highly complex media practices and mediated life worlds of individuals has become highly challenging, both in theoretical and methodological terms. From an empirical point of view, diary methods, and particularly
Anna Wagner   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

UK demand for hyperlocal media [PDF]

open access: yes, 2013
In March 2012, Nesta published Here and now, the first landscape review of hyperlocal media in the UK. Since then, they have continued our programme of practical experimentation and research, called Destination Local, to develop a strong ...

core  

Impact of pandemic proximity and media use on risk perception during COVID-19 in China

open access: yesGeomatics, Natural Hazards & Risk, 2022
Do people in other areas perceive less risk from the COVID-19 pandemic than those in Hubei Province in the pandemic area? Do people in communities with COVID-19 infections perceive a higher level of risk of the virus?
Shuhuan Zhou
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Media Use and Political Engagement: Cross-Cultural Approaches| Media Use and Political Engagement: Cross-Cultural Approaches—Introduction

open access: yesInternational Journal of Communication, 2023
Democracies around the world are struggling with the decline of civic and political engagement. At the same time, new forms of engagement such as lifestyle politics, Internet activism, and political consumerism are on the rise.
Özen Odağ   +3 more
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Social Media Use in Crises and Risks: An Introduction to the Collection [PDF]

open access: yes, 2018
This book is about how different communicators – whether professionals, such as crisis managers, first responders and journalists, or private citizens and disaster victims – have used social media to communicate about risks and crises.
Backholm, Klas   +3 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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