Results 71 to 80 of about 6,828,197 (312)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Bridging the gap: the impact of parental education and child leisure activities on cognitive and socioemotional skills in preschoolers

open access: yesFrontiers in Psychology
Family socioeconomic status is broadly acknowledged to be associated with child development and wellbeing. However, the extent of this association across various dimensions of child development remains a topic of ongoing debate.
Arina Shatskaya   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Healthy Ageing and Mediated Health Expertise

open access: yesNordicom Review, 2017
The media are, for many older people, one of the most important sources of information about health. In this article, I examine older people’s experiences and use of media to acquire knowledge about health issues relating to their own life. Key questions
Christensen Christa Lykke
doaj   +1 more source

Fair Use and Social Media

open access: yes, 2018
This poster was created in a collaborative effort by Musselman Library’s Copyright Committee as part of a display for Fair Use Week 2018. The poster was intended to get viewers to think about the 4 factors of fair use in the context of two art projects ...
Dettinger, John
core  

Social Media Strategic Plan For Under Armour [PDF]

open access: yes, 2014
This thesis is a study of the effects of social media on an organization’s integrated marketing communications strategy in general and provides a proposal of how the sports apparel company Under Armour could use social media to enhance its promotional ...
Leers, Ashley
core   +2 more sources

Transillumination imaging through scattering media by use of photorefractive polymers [PDF]

open access: yes, 1998
We demonstrate the use of a near-infrared-sensitive photorefractive polymer with high efficiency for imaging through scattering media, using an all-optical holographic time gate. Imaging through nine scattering mean free paths is performed at 800 nm with
Kippelen, B.   +6 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The NLRB’s Social Media Guidelines a Lose-Lose: Why the NLRB’s Stance on Social Media Fails to Fully Address Employer’s Concerns and Dilutes Employee Protections [PDF]

open access: yes, 2013
[Excerpt] The expanding use of both personal and professional social media sites has resulted in its growing impact in the workplace. Recently, many examples have emerged where an individual’s use of social media for communicating frustrations or sharing
Chris, Schlag
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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