Frequency-Dependent Plasticity in the Temporal Association Cortex Originates from the Primary Auditory Cortex, and Is Modified by the Secondary Auditory Cortex and the Medial Geniculate Body. [PDF]
J Neurosci, 2022 The brain areas that mediate the formation of auditory threat memory and perceptual decisions remain uncertain to date. Candidates include the primary (A1) and secondary (A2) auditory cortex, the medial division of the medial geniculate body (MGm ...
Luo B +7 more
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Aberrant Auditory Steady-State Response of Awake Mice After Single Application of the NMDA Receptor Antagonist MK-801 Into the Medial Geniculate Body. [PDF]
Int J Neuropsychopharmacol, 2020 Background Systemic administration of noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonists such as MK-801 is widely used to model psychosis of schizophrenia (SZ).
Wang X, Li Y, Chen J, Li Z, Li J, Qin L.
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Corticothalamic projections deliver enhanced responses to medial geniculate body as a function of the temporal reliability of the stimulus. [PDF]
J Physiol, 2021 Aging and challenging signal-in-noise conditions are known to engage use of cortical resources to help maintain speech understanding. Extensive corticothalamic projections are thought to provide attentional, mnemonic and cognitive-related inputs in ...
Kommajosyula SP +4 more
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Kv4.2-Positive Domains on Dendrites in the Mouse Medial Geniculate Body Receive Ascending Excitatory and Inhibitory Inputs Preferentially From the Inferior Colliculus. [PDF]
Front Neurosci, 2021 The medial geniculate body (MGB) is the thalamic center of the auditory lemniscal pathway. The ventral division of MGB (MGV) receives excitatory and inhibitory inputs from the inferior colliculus (IC).
Fujimoto H +6 more
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Cholinergic and non-cholinergic projections from the pedunculopontine and laterodorsal tegmental nuclei to the medial geniculate body in guinea pigs [PDF]
Frontiers in Neuroanatomy, 2010 The midbrain tegmentum is the source of cholinergic innervation of the thalamus and has been associated with arousal and control of the sleep/wake cycle. In general, the innervation arises bilaterally from the pedunculopontine tegmental nucleus (PPT) and
Susan D Motts +3 more
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Inhibition of Experimental Tinnitus With High Frequency Stimulation of the Rat Medial Geniculate Body. [PDF]
Neuromodulation, 2019 Neuromodulation is a promising treatment modality for tinnitus, especially in chronic and severe cases. The auditory thalamus plays a key role in the pathophysiology of tinnitus, as it integrates and processes auditory and limbic information.
van Zwieten G +7 more
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Effect of auditory cortex deactivation on stimulus-specific adaptation in the medial geniculate body. [PDF]
J Neurosci, 2011 An animal's survival may depend on detecting new events or objects in its environment, and it is likely that the brain has evolved specific mechanisms to detect such changes.
Antunes FM, Malmierca MS.
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Cholinergic cells in the tegmentum send branching projections to the inferior colliculus and the medial geniculate body. [PDF]
Neuroscience, 2011 Motts SD, Schofield BR.
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Preservation of temporal information in the medial geniculate body [PDF]
The Journal of the Acoustical Society of America, 1979 Persistance in the medial geniculate body (MGB) of spike discharges synchronized with the phase of low frequency tones was investigated in cats anaesthetized with nitrous oxide. Only one out of ten single units responded to tone in a sustained manner. Eighty-eight of these units were analysed with high resolution interval and period histograms.
F. de Ribaupierre +2 more
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Evolution of GABAergic circuitry in the mammalian medial geniculate body. [PDF]
Proceedings of the National Academy of Sciences, 1996 Many features in the mammalian sensory thalamus, such as the types of neurons, their connections, or their neurotransmitters, are conserved in evolution. We found a wide range in the proportion of gamma-aminobutyric acidergic (GABAergic) neurons in the medial geniculate body, from <1% (bat and rat) to 25% or more (cat and monkey).
Jeffery A. Winer, David T. Larue
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