Results 71 to 80 of about 8,251 (204)
AAV‐PHP.eB Peripheral Delivery and Central Expression in Cre Mice
Journal of Comparative Neurology, Volume 534, Issue 1, January 2026.Retro‐orbital injection of AAV‐PHP.eB‐FLEX‐tdTomato into four different strains of Cre mice produced various and distinct patterns of transduction efficiency and tropism across brain regions and cell types. We found many target neurons expressing tdTomato in most but not all strains, along with a low level of nonspecific (Cre‐independent) expression ...
Haidong Zhu, Joel C. Geerling
wiley +1 more source
Dual AAV gene therapy achieves recovery of hearing and auditory processing in a DFNB16 mouse model
Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.DFNB16 is among the most prevalent forms of congenital deafness, caused by mutations in the Stereocilin gene. Although no treatment currently exists, gene therapy represents a promising curative approach. Here, we demonstrate that AAV‐mediated gene delivery in a DFNB16 mouse model restored both peripheral hearing and central auditory processing ...
Sepideh Iranfar +12 more
wiley +1 more source
The Visual Umwelt of primates and Hippocampal Representations of Space
Hippocampus, Volume 36, Issue 1, January 2026.ABSTRACT Evolution sculpts the brain's sensory adaptations. Because these adaptations differ markedly across species, it is challenging for humans to fully comprehend how other animals perceive the world. For a nocturnal mouse, the subjective sensory world—its Umwelt—is dominated by odors, sounds, and textures, with visual input playing a secondary ...
J. Martinez‐Trujillo, D. Piza
wiley +1 more source
Hydrogel Microspheres for Biomedical Applications
Small Science, Volume 6, Issue 1, January 2026.Hydrogel microspheres (HMs) play pivotal roles in biomedical applications, such as drug delivery, cell culture, regenerative medicine, wound healing, and tumor immunity. This review focuses on the latest findings to provide a more comprehensive understanding of HMs for biomedical applications.
Yingkang Huang +11 more
wiley +1 more source
Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale
Geriatrics &Gerontology International, Volume 26, Issue 1, January 2026.ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi +4 more
wiley +1 more source
Exploring functions for the non-lemniscal auditory thalamus
Frontiers in Neural Circuits, 2015 The functions of the medial geniculate body (MGB) in normal hearing still remain somewhat enigmatic, in part due to the relatively unexplored properties of the non-lemniscal MGB nuclei.
Charles C Lee
doaj +1 more source
Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways
Advanced Science, Volume 12, Issue 46, December 11, 2025.Decoding sound from neural activity in mice reveals a striking shift in how the brain encodes sound: from precise but redundant timing codes in early auditory areas to efficient, synergistic rate‐based codes in the cortex. This transformation highlights a robust neural strategy for turning complex acoustic input into coherent perception across the ...
Alexa Buck +7 more
wiley +1 more source
Behavioural Neurology, 2003 A variety of involuntary speech phenomena as for example palilalia have been described as consequences of neurological disorders. Palilalia is the involuntary repetition of syllabels, words and phrases in ongoing speech.
T. Dietl +4 more
doaj +1 more source
The extraction of frequency information from electrical stimulation of the medial geniculate body.
, 2021 Frederick W. Mis
openalex +2 more sources
Neurogenic Stem Cell Niche in the Auditory Thalamus: In Vitro Evidence of Neural Stem Cells in the Rat Medial Geniculate Body. [PDF]
Life (Basel), 2023 Engert J +5 more
europepmc +1 more source