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The Medial Temporal Lobe Memory System [PDF]

Science, 1991
Studies of human amnesia and studies of an animal model of human amnesia in the monkey have identified the anatomical components of the brain system for memory in the medial temporal lobe and have illuminated its function. This neural system consists of the hippocampus and adjacent, anatomically related cortex, including entorhinal, perirhinal, and ...
L R, Squire, S, Zola-Morgan
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Representing Representation: Integration between the Temporal Lobe and the Posterior Cingulate Influences the Content and Form of Spontaneous Thought. [PDF]

PLoS ONE, 2016
When not engaged in the moment, we often spontaneously represent people, places and events that are not present in the environment. Although this capacity has been linked to the default mode network (DMN), it remains unclear how interactions between the ...
Jonathan Smallwood, Theodoros Karapanagiotidis, Florence Ruby, Barbara Medea, Irene de Caso, Mahiko Konishi, Hao-Ting Wang, Glyn Hallam, Daniel S Margulies, Elizabeth Jefferies   +9 more
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Medial temporal lobe and topographical memory [PDF]

Proceedings of the National Academy of Sciences, 2017
Significance We investigated the role of the medial temporal lobe (MTL) in topographical memory. Participants studied a scene depicting four hills of different shapes and sizes and made a choice among four test images. MTL patients were impaired in a Rotation condition where the correct choice depicted the study scene from a shifted ...
Zhisen J, Urgolites, Ramona O, Hopkins, Larry R, Squire   +2 more
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Medial temporal lobe atrophy in patients with refractory temporal lobe epilepsy [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2003
The objective of this study was to assess the volumes of medial temporal lobe structures using high resolution magnetic resonance images from patients with chronic refractory medial temporal lobe epilepsy (MTLE).We studied 30 healthy subjects, and 25 patients with drug refractory MTLE and unilateral hippocampal atrophy (HA).
L, Bonilha, E, Kobayashi, C, Rorden, F, Cendes, L M, Li   +4 more
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Medial Temporal Lobe Activation in Learning

Pediatric Neurology Briefs, 1998
Regional cerebral blood flow was examined by PET recordings during multiple-trial learning in healthy volunteers tested at Guy’s and St Thomas’s Hospitals and the MRC Cyclotron Unit, Hammersmith Hospital, London.
J Gordon Millichap
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Neonatal subpial hemorrhage along the medial side of the temporal lobe: Two case reports

Radiology Case Reports, 2022
Neonatal subpial hemorrhage has been underrecognized until recently and its pathophysiology remains unclear. Advances in magnetic resonance imaging have facilitated the identification of hemorrhage within the subpial space and cohort studies recently ...
Naoko Matsubara, MD, Mitsunori Kanagaki, MD, PhD, Shuichi Ito, MD, Chieko Matsushima, MD, Minako Ide, MD, Ritsuko Kitamura, MD, Yoshinobu Nishida, MD, Yoshinobu Akasaka, MD, PhD   +7 more
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The Necessity of the Medial Temporal Lobe for Statistical Learning [PDF]

Journal of Cognitive Neuroscience, 2014
AbstractThe sensory input that we experience is highly patterned, and we are experts at detecting these regularities. Although the extraction of such regularities, or statistical learning (SL), is typically viewed as a cortical process, recent studies have implicated the medial temporal lobe (MTL), including the hippocampus. These studies have employed
Anna C. Schapiro, Emma Gregory, Barbara Landau, Michael McCloskey, Nicholas B. Turk-Browne   +4 more
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Long-term coding of personal and universal associations underlying the memory web in the human brain

Nature Communications, 2016
Neurons in the medial temporal lobe change their firing patterns as people learn to pair items together, yet it is unclear if this pairing lasts. Here, authors find that single medial temporal lobe neurons in humans tend to respond similarly to items ...
Emanuela De Falco, Matias J. Ison, Itzhak Fried, Rodrigo Quian Quiroga   +3 more
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Decoding representations of scenes in the medial temporal lobes [PDF]

Hippocampus, 2011
AbstractRecent theoretical perspectives have suggested that the function of the human hippocampus, like its rodent counterpart, may be best characterized in terms of its information processing capacities. In this study, we use a combination of high‐resolution functional magnetic resonance imaging, multivariate pattern analysis, and a simple decision ...
Bonnici, Heidi M, Kumaran, Dharshan, Chadwick, Martin J, Weiskopf, Nikolaus, Hassabis, Demis, Maguire, Eleanor A   +5 more
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Functional Specialization in the Human Medial Temporal Lobe [PDF]

The Journal of Neuroscience, 2005
Investigations of memory in rats and nonhuman primates have demonstrated functional specialization within the medial temporal lobe (MTL), a set of heavily interconnected structures including the hippocampal formation and underlying entorhinal, perirhinal, and parahippocampal cortices.
Barense, Morgan D, Bussey, Timothy J, Lee, Andy CH, Rogers, Timothy T, Davies, R Rhys, Saksida, Lisa M, Murray, Elisabeth A, Graham, Kim S   +7 more
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