Results 41 to 50 of about 1,504 (212)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Effects of Level of Retrieval Success on Recall-Related Frontal and Medial Temporal Lobe Activations

Behavioural Neurology, 2002
Brain dedicated single photon emission computed tomography (SPECT) was used to compare the neuroactivation produced by the cued recall of response words in a set of studied word pairs with that produced by the cued retrieval of words semantically related
Daniela Montaldi, Andrew R. Mayes, Anna Barnes, Donald M. Hadley, Jim Patterson, David J. Wyper   +5 more
doaj   +1 more source

Mesial temporal sclerosis presented with refractory seizure

APIK Journal of Internal Medicine, 2019
Background: Refractory complex partial seizures are common in temporal lobe epilepsy, which is often associated with sclerosis of the structures of the medial temporal lobes, particularly the hippocampus.
Malav Patel, Rishika Reddy, Sangram Biradar, V H Kumarswamy   +3 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Progress update from the hippocampal subfields group

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2019
Introduction Heterogeneity of segmentation protocols for medial temporal lobe regions and hippocampal subfields on in vivo magnetic resonance imaging hinders the ability to integrate findings across studies.
Rosanna K. Olsen, Valerie A. Carr, Ana M. Daugherty, Renaud La Joie, Robert S.C. Amaral, Katrin Amunts, Jean C. Augustinack, Arnold Bakker, Andrew R. Bender, David Berron, Marina Boccardi, Martina Bocchetta, Alison C. Burggren, M. Mallar Chakravarty, Gaël Chételat, Robin deFlores, Jordan DeKraker, Song‐Lin Ding, Mirjam I. Geerlings, Yushan Huang, Ricardo Insausti, Elliott G. Johnson, Prabesh Kanel, Olga Kedo, Kristen M. Kennedy, Attila Keresztes, Joshua K. Lee, Ulman Lindenberger, Susanne G. Mueller, Elizabeth M. Mulligan, Noa Ofen, Daniela J. Palombo, Lorenzo Pasquini, John Pluta, Naftali Raz, Karen M. Rodrigue, Margaret L. Schlichting, Yee Lee Shing, Craig E.L. Stark, Trevor A. Steve, Nanthia A. Suthana, Lei Wang, Markus Werkle‐Bergner, Paul A. Yushkevich, Qijing Yu, Laura E.M. Wisse, Hippocampal Subfields Group   +46 more
doaj   +1 more source

Feasibility of the Medial Temporal lobe Atrophy index (MTAi) and derived methods for measuring atrophy of the medial temporal lobe

Frontiers in Aging Neuroscience, 2014
Introduction: the Medial Temporal-lobe Atrophy index (MTAi), 2D-Medial Temporal Atrophy (2D-MTA), yearly rate of MTA (yrRMTA) and yearly rate of relative MTA (yrRMTA) are simple protocols for measuring the relative extent of atrophy in the MTL in ...
Francisco eConejo Bayón, Jesús eMaese, Aníbal eFernandez Oliveira, Tamara eMesas, Estíbaliz eHerrera de la Llave, Tania eÁlvarez Avellón, Manuel eMenéndez-González, Manuel eMenéndez-González, Manuel eMenéndez-González   +8 more
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Evolving perspectives of medial temporal memory function: hippocampal processes in visual and auditory forms of episodic and working memory

Frontiers in Cognition
A cornerstone of memory science is the finding that the medial temporal lobe plays a critical role in supporting episodic long-term memory. However, the role that this brain region plays in supporting other forms of memory such as working memory is ...
Chris Hawkins, Andrew P. Yonelinas
doaj   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source