The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source
Intraneural Venous Malformations of the Median Nerve
Venous malformations arising from the peripheral nerve are a rare type of vascular malformation. We present the first case of an intraneural venous malformation of the median nerve to be reported in a child and review the previous two cases of median ...
Sara Alicia González Porto +2 more
doaj +1 more source
Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita +3 more
wiley +1 more source
Nerve conduction studies of median nerve in normal subjects
Objective: To establish the normal electrophysiological values of the median nerve in normal healthy adult subjects. Material and Methods: Nerve conduction study was performed on the median nerve of 100 screened healthy adult volunteers using standard ...
W Permsirivanich, A Boonmeeprakob
doaj
The effect of wrist braces on current perception threshold (CPT) among female data processing operators in Malaysia [PDF]
A cross sectional study was conducted to evaluate the effect of wrist braces on current perception threshold value of median nerve among female data processing operators (n = 48).
Ismail, Syazwan Aizat +4 more
core
Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley +1 more source
The Organization and Role During Locomotion of the Proximal Musculature of the Cricket Foreleg : I. Anatomy and Innervation [PDF]
The structure of the proximal segments of the cricket (Gryllus bimaculatus) foreleg, together with the associated musculature and its innervation are described.
Laurent, Gilles, Richard, Daniel
core
Intravenous infusion of magnesium sulfate and its effect on horses with trigeminal-mediated headshaking. [PDF]
BackgroundTrigeminal-mediated headshaking results from low-threshold firing of the trigeminal nerve resulting in apparent facial pain. Magnesium may have neuroprotective effects on nerve firing that potentially dampen signs of neuropathic pain.
Aleman, Monica +5 more
core +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source

