Results 61 to 70 of about 151,746 (310)

Facial, Cervical, and Mediastinal Emphysema of the Clarinet Player: Case Report

Balkan Medical Journal, 2014
Background: Cervicofacial emphysema may arise due to the leakage of air from a defect in the aerodigestive tract to the fascial layers of neck and face. Rarely, it may be caused by insufflation of air through the Stensen’s duct.
Yusuf Özgür Biçer, Selcan Kesgin, Erkan Tezcan, Serap Köybaşı   +3 more
doaj   +1 more source

One Case about Primary Mediastinal Primary Mediastinal Tumor 
with Mediastinal Sarcoma and Literature Review

, 2016
Primary mediastinal seminoma is a kind of germ cell malignancy outside the gonads, and it’s rarer with sarcoma component. This disease which has no special clinical manifestations and imaging characteristics is difficult to identify with other ...
Qingxin LI, Jinchen DU, Yulian BAN, Qunqun LI, Dong CHAO   +4 more
core   +1 more source

Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild‐to‐moderate asthma

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin and is approved for adolescents and adults with severe asthma. This analysis assessed pharmacokinetics (PK), pharmacodynamics and safety of tezepelumab up to 85 days postdose in adolescents and children.
Anna Lundahl, Jonathan Grigg, Lubna Abuqayyas, Piotr Kuna, Gillian Hunter, Beata Pawlikowska, Jacob Leander, Michael Levin, Atul Gupta, James Paton, Katharine C. Pike, Jane R. Parnes, Gun Almqvist, Stephanie L. Roseti, on behalf of the study investigators   +14 more
wiley   +1 more source

The effect of mild and moderate hepatic impairment on the pharmacokinetics, safety and tolerability of balcinrenone

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson, Deeyen Karsanji, Bonifride Tuyishimire, Joanna Parkinson, Maria Heijer, Tadeusz Pawlik, Judith Hartleib‐Geschwindner, Maria Leonsson‐Zachrisson, Hans Ericsson   +8 more
wiley   +1 more source

Multi-Level Oncological Management of a Rare, Combined Mediastinal Tumor: A Case Report

Current Oncology
Malignant mediastinal tumors are a group representing some of the most demanding oncological challenges for early, multi-level, and successful management.
Vasileios Theocharidis, Thomas Rallis, Apostolos Gogakos, Dimitrios Paliouras, Achilleas Lazopoulos, Meropi Koutourini, Myrto Tzinevi, Aikaterini Vildiridi, Prokopios Dimopoulos, Dimitrios Kasarakis, Panagiotis Kousidis, Anastasia Nikolaidou, Paraskevas Vrochidis, Maria Mironidou-Tzouveleki, Nikolaos Barbetakis   +14 more
doaj   +1 more source

Tumor neuroendocrino primario mediastinal [PDF]

, 2020
This the case of a 49-year-old male patient with no relevant history or harmful habits, chest pain, light-effort dyspnoea and anterior mediastinal mass.
Indacochea-Cáceda, Sonia, García-Ramos, Hugo Michael, Luque-Quispe, Carlos   +2 more
core   +1 more source

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

The Impact of Aging on the Anatomical Course of the Azygos Vein: A Retrospective, Computed Tomography Study

Clinical Anatomy, EarlyView.
ABSTRACT The azygos vein (AV) is typically described as ascending vertically to the right of the vertebral column before arching anteriorly to drain into the superior vena cava. However, a small number of studies suggest that it is found leftward in older adults.
Lauren R. Hector, Hania Paverd, Arthikkaa Thavakumar, Cecilia Brassett, Timothy J. Sadler   +4 more
wiley   +1 more source

Efficacy of On-Site Evaluation in EBUS-Guided Transbronchial Needle Aspiration Versus Cell Block

Journal of Islamic International Medical College
Objective: To determine Rapid onsite evaluation (ROSE) effectiveness, sensitivity and specificity during Endoscopic ultrasound guided Transbronchial needle aspiration (EBUS TBNA) and compare it with cell blocks prepared during same process. Study Design:
Motia Kanwal , Anum Usman , Hafsa Waseem , Fakhra Noureen , Ama Tul Naval , Ayesha Sarwar
doaj   +1 more source

Observations on Two Previously Unreported Anatomical Factors Relating to the Esophagogastric Junction

Clinical Anatomy, EarlyView.
ABSTRACT The esophagogastric junction (EGJ) is the anatomical zone where the esophagus ends and the stomach begins. Its competence in preventing gastro‐esophageal reflux has been shown to depend on a number of factors which have been extensively investigated and widely accepted.
Yuhan Guo, Chandan Sekhon, Jason Sparks, Jonathan Brown, Cecilia Brassett   +4 more
wiley   +1 more source