Results 71 to 80 of about 151,746 (310)

Case Report - Idiopathic mediastinal fibrosis presenting as mediastinal compression syndrome

open access: yes, 2005
Mediastinal compression syndrome is a commonly seen entity. Mediastinal compression, mostly due to a space-occupying lesion, is distinct and different from mediastinitis/mediastinal fibrosis, which could also lead to superior vena cava syndrome ...
Harsha R. Salkar, Prashant L. Patil
core   +2 more sources

Special Populations in Pivotal Clinical Trials: Eligibility and Supporting Evidence for Exclusion in EMA‐Authorised Medicines

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Evidence on the efficacy and safety of medicines supporting marketing authorization is largely derived from randomized controlled trials, yet these trials often exclude populations likely to use the medications in clinical practice. This study assessed eligibility of special populations, defined as pregnant and breast‐feeding individuals, elderly ...
Maja J. Jørgensen   +2 more
wiley   +1 more source

Primary extragonadal germ cell tumours: Real‐world data from a high‐volume centre

open access: yesBJUI Compass
Objectives To provide improved evidence for treatment recommendations, this study analysed real‐world data on the characteristics, treatment and prognosis of primary extragonadal germ cell tumours (EGCTs), a very rare cancer entity that shares ...
Marc Kidess   +17 more
doaj   +1 more source

Primary Pulmonary Mesenchymal Neoplasm With EWSR1::CREM Fusion: Cytologic Findings and Molecular Diagnosis

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Background Primary pulmonary mesenchymal neoplasms with EWSR1::CREM fusion are rare. These lesions are challenging to diagnose by morphology and immunohistochemistry alone. Case A 66‐year‐old woman (ex‐smoker) was found to have a 1.3‐cm right lower lobe lung nodule that had grown very slowly over a 9‐year period.
Priya Upadhyay   +2 more
wiley   +1 more source

Case report: Epidermoid cyst misdiagnosed as a loculated pericardial effusion

open access: yesIndian Journal of Radiology and Imaging, 2008
A 25-year old man presented with a mediastinal lesion which was initially diagnosed as a loculated pericardial collection on echocardiography. Subsequent imaging showed it to be a cystic mediastinal mass, and following surgery and histopathology, it ...
NC Sharma, Anshu Sharma, Manish Bajaj
doaj   +1 more source

Mediastinal Ectopic Thyroid Carcinoma and Concurrent Multinodular Pulmonary Fibrosis in a Horse

open access: yes, 2019
A 30-year-old Standardbred gelding was referred for chronic pleural effusion. Thoracic ultrasound revealed marked bilateral pleural effusion and a large heterogeneous mass within the cranial mediastinum, which extended from the right 5th to the 11th ...
García Fernández, Rosa Ana   +4 more
core   +1 more source

Utility of Fine Needle Aspiration Supernatant for Real‐Time PCR–Based Mutation Analysis in Non–Small Cell Lung Cancer

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Background The emergence of personalized therapy and molecular sequencing has significantly transformed the management of advanced non–small cell lung carcinoma (NSCLC). Supernatants obtained from fine needle aspiration (FNA) have been shown to be a reliable source of high‐quality nucleic acid for molecular testing.
Adeyinka Akinsanya   +9 more
wiley   +1 more source

Successful treatment of primary mediastinal malignant germ cell tumor with multiple systemic metastases in children using multi-drug combination chemotherapy: a rare case report

open access: yesFrontiers in Pharmacology
Primary mediastinal malignant germ cell tumors (PMMGCTs) in children are highly aggressive and associated with a poor prognosis. We herein report the case of a male pediatric patient who presented with a large mediastinal mass and extensive metastases to
Yang-Yang Jiao   +8 more
doaj   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli   +17 more
wiley   +1 more source

Minimally Invasive Sampling of Mediastinal Lesions

open access: yesLife
This narrative review examines the existing literature on minimally invasive image-guided sampling techniques of mediastinal lesions gathered from international databases (Medline, PubMed, Scopus, and Google Scholar). Original studies, systematic reviews
Alberto Fantin   +11 more
doaj   +1 more source

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