Results 61 to 70 of about 81,676 (316)

Clonal Evolution and Lineage Switch from T-Cell Acute Lymphoblastic Leukemia to Acute Myeloid Leukemia in Therapy-Resistant <i>PICALM::MLLT10</i> Leukemia. [PDF]

EJHaem
ABSTRACT Background PICALM::MLLT10‐positive T‐ALL is rare and associated with poor prognosis. Lineage switch to AML is exceptionally uncommon, particularly after long‐term remission. Case Presentation We report an adolescent PICALM::MLLT10‐positive T‐ALL with a cortical thymocyte, non‐ETP phenotype.
Kawamura M, Sadato D, Haruta M, Kubota N, Harada Y, Kobayashi T, Doki N, Kasai F, Nishimura Y, Kobayashi H, Maseki N.   +10 more
europepmc   +2 more sources

Intracerebral haemorrhage in a dog with steroid-responsive meningitis arteritis [PDF]

, 2017
A one-year and six-month-old female neutered Boxer dog was presented with a four-day history of pyrexia, lethargy and neck pain. An intracerebral haemorrhage and a mediastinal mass were identified.
Brocal, Josep, Gutierrez-Quintana, Rodrigo, Hammond, Gawain, José López, Roberto   +3 more
core   +1 more source

Risk Factors for Anastomotic Stricture and Obstructive Symptoms Following Double‐Flap Technique Reconstruction After Proximal Gastrectomy

Annals of Gastroenterological Surgery, EarlyView.
This retrospective study investigated risk factors for anastomotic stricture and obstructive symptoms following double‐flap technique (DFT) reconstruction after proximal gastrectomy. Mucosal detachment, potentially caused by thermal damage, was identified as a significant risk factor for anastomotic stricture, while continuous suturing at the esophago ...
Shinji Kuroda, Yoshihiko Kakiuchi, Satoru Kikuchi, Hajime Kashima, Nobuhiko Kanaya, Shunya Hanzawa, Kenjiro Kumano, Masahiko Nishizaki, Shunsuke Kagawa, Toshiyoshi Fujiwara   +9 more
wiley   +1 more source

Science, medicine, and the future. Prospecting for gold in the human genome [PDF]

, 1997
Doctors struggling with the daily problems of clinical medicine usually have little time for molecular and cell biology. But genetic research is producing an explosion of knowledge which doctors will need to understand in order to join in the ethical and
Savill, John
core   +2 more sources

Bronchial artery aneurysm presenting with epigastric pain that improves with vomiting

Respirology Case Reports, 2022
A 64‐year‐old man presented to the emergency department with a chief complaint of epigastric pain that improved with vomiting. He was initially treated for gastrointestinal disease, but computed tomography (CT) showed a mediastinal haematoma and contrast‐
Kazuki Hayashi, Jun Hanaoka, Yusuke Kita
doaj   +1 more source

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman, Mathieu Félices, Bhaskar Pandurangavittal, Sanman Ghorpade, Caroline Easterbrook, Marcin Zabielski, Oscar Della Pasqua   +6 more
wiley   +1 more source

A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]

, 2010
Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Bernadet, Philippe, Bernard, Julie, Bernex, Florence, Castagné, Nathalie, Deplanche, Martine, Deville, Sébastien, Dubosclard, Virginie, Dubuquoy, Catherine, Durand, Guillaume, Eléouët, Jean-François, Meyer, Gilles, Petit-Camurdan, Agnès, Riffault, Sabine, Schwartz-Cornil, Isabelle, Soulestin, Marion   +14 more
core   +2 more sources

Early kinetics of intestinal infection and immune responses to two Toxoplasma gondii strains in pigs [PDF]

, 2020
Toxoplasma gondiiis an obligate intracellular parasite, able to infect all homeothermicanimals mostly through ingestion of (oo)cysts contaminated food or water. Recently,we observed aT.
Cox, Eric, De Craeye, Stéphane, Devriendt, Bert, Dierick, Katelijne, Dorny, Pierre, Gisbert Algaba, Ignacio, Jennes, Malgorzata, Rahman, Mizanur   +7 more
core   +1 more source

Analysis of SWI Complex Subunits in 69 Cases of TTF‐1 Negative Non‐Small Cell Lung Carcinoma

Diagnostic Cytopathology, EarlyView.
ABSTRACT Non‐small cell lung carcinomas, not otherwise specified (NSCLC‐NOS) with a specific signature including high‐grade hepatoid/clear cell morphology, negative lung panel mutational analysis, negative TTF‐1/Napsin A staining can be reported as a morphologic variant of an aggressive carcinoma with loss of one of the subunits of the SWI/SNF ...
Ramin Zargham, Feng (Selina) Ji, Tarek Bismar   +2 more
wiley   +1 more source

EBUS-guided cryobiopsy in the diagnosis of thoracic disorders

Pulmonology
Background Endobronchial Ultrasound (EBUS) has emerged as a crucial tool for diagnosing intrathoracic disorders, particularly in the staging of lung cancer.
V. Poletti, S. Petrarulo, S. Piciucchi, A. Dubini, A.J. De Grauw, F. Sultani, S. Martinello, H.K. Gonunguntla, C. Ravaglia   +8 more
doaj   +1 more source