Results 81 to 90 of about 9,066,717 (393)

PCSK9 Promotes the Malignancy of Triple‐negative Breast Cancer Cells by Reducing Cholesterol Levels at the Plasma Membrane to Activate EGFR and HER3

Advanced Science, EarlyView.
By decreasing cholesterol and lipid raft levels in the plasma membrane, proprotein convertase subtilisin/kexin type 9 (PCSK9) boosts human epidermal growth factor receptor 1 and 3 (EGFR and HER3) activation, driving tumor growth and metastasis in triple‐negative breast cancer (TNBC).
Tianhong Li, Renfei Wu, Kathy Qian Luo
wiley   +1 more source

Comparison of machine learning methods for classifying mediastinal lymph node metastasis of non-small cell lung cancer from 18F-FDG PET/CT images [PDF]

, 2017
The present study shows that the performance of CNN is not significantly different from the best classical methods and human doctors for classifying mediastinal lymph node metastasis of NSCLC from PET/CT images. Because CNN does not need tumor segmentation or feature calculation, it is more convenient and more objective than the classical methods ...
arxiv   +1 more source

A CASE OF MEDIASTINAL HODGKIN'S DISEASE

The journal of the Japanese Practical Surgeon Society, 1992
A 16-year-old female visited our hospital because of a mass on the neck. On physical examination, masses were palpated in the left supraclavicular fossa and on the left anterior chest wall. Biopsy studies provided no definitive diagnosis, and exploratory operation was carried out.
Kazuya Nakaoka, Sin Mizutani, Masanobu Hayakawa, Tetsuto Takao   +3 more
openaire   +3 more sources

Prognostic factors for patients with esophageal cancer who achieve pathological complete response in the primary tumor after upfront chemotherapy or chemoradiotherapy

Annals of Gastroenterological Surgery, EarlyView.
Male gender and pathological lymph node metastasis are independent poor prognostic factors in patients with esophageal cancer who receive upfront treatment followed by surgery and achieved pathological complete response of the primary tumor. Among patients without pathological lymph node metastasis, the upfront chemotherapy group showed significantly ...
Masaaki Motoori, Koji Tanaka, Hiroshi Miyata, Makoto Yamasaki, Osamu Shiraishi, Atsushi Takeno, Tomoki Makino, Keijiro Sugimura, Takushi Yasuda, Yuichiro Doki   +9 more
wiley   +1 more source

Isolated middle mediastinal mass associated with immunoglobulin G4-related disease

Surgical Case Reports, 2021
Background Immunoglobulin G4-related disease (IgG4-RD) is a multi-organ disorder predominantly occurring in middle-aged to elderly male patients characterized by multi-organ fibrosis, specific pathological findings of storiform fibrosis with IgG4 ...
Haruaki Hino, Noriyuki Tanaka, Hiroshi Matsui, Takahiro Utsumi, Natsumi Maru, Yohei Taniguchi, Tomohito Saito, Kouji Tsuta, Tomohiro Murakawa   +8 more
doaj   +1 more source

Salvage esophagectomy for unresectable locally advanced esophageal squamous cell carcinoma: Significant or not?

Annals of Gastroenterological Surgery, EarlyView.
Abstract We reviewed the current status and perspectives on salvage esophagectomy for initially unresectable locally advanced esophageal squamous cell carcinoma (ESCC) in the era of minimally invasive surgery and immunotherapy. Although the standard treatment for these patients is definitive chemoradiotherapy (CRT), the complete response rate to CRT ...
Hiroshi Saeki, Makoto Sakai, Takayoshi Watanabe, Makoto Sohda, Ken Shirabe   +4 more
wiley   +1 more source

Skeletal muscle dissemination in a dog with T‐cell lymphoma

Veterinary Medicine and Science, Volume 9, Issue 1, Page 53-58, January 2023., 2023
Skeletal muscles metastases are considered quite rare in small animals. When it occurs, muscle metastases typically involve paravertebral muscle and hind limb. Whole‐body CT is of paramount importance in patients affected by neoplasms with potential systemic metastases.
Tommaso Magni, Francesca Del Signore, Massimo Vignoli, Rossella Terragni, Alessandro Poli, Francesca Parisi, Michele Sampaolo, Andrea Boari, Arianna Miglio, Paolo Emidio Crisi   +9 more
wiley   +1 more source

Incidental chest radiographic findings in adult patients with acute cough [PDF]

, 2012
PURPOSE Imaging may produce unexpected or incidental findings with consequences for patients and ordering of future investigations. Chest radiography in patients with acute cough is among the most common reasons for imaging in primary care, but data on ...
Almirall, Jordi, Blasi, Francesco, Broekhuizen, Lidewij, Butler, Christopher, Chlabicz, Slawomir, Coenen, Samuel, Davies, Mel, de Jong, Pim, De Sutter, An, Godycki-Cwirko, Maciek, Goossens, Herman, Hood, Kerenza, Hupkova, Helena, Kersnik, Janko, Little, Paul, Mierzecki, Arthur, Moore, Michael, Mölstad, Sigvard, Schaberg, Tom, Torres, Antoni, Touboul, Pia, van Vugt, Saskia, Verheij, Theo, Zuithoff, Nicolaas   +23 more
core   +1 more source

Mediastinal masses—transthoracic ultrasonography aspects

Medicine, 2017
Mediastinal masses are usually assessed by computer tomography (CT) and magnetic resonance imaging (MRI). Transthoracic ultrasonography (TUS) can also provide useful information concerning prevascular and posterior mediastinal masses abutting the ...
R. Chira, A. Chira, P. Mircea, S. Valean
semanticscholar   +1 more source

Influence of Facility Size on Perioperative Outcomes in Minimally Invasive Esophagectomy for 14 152 Patients With Esophageal Cancer Based on the Japanese National Clinical Database: A Multicenter Cohort Study

Annals of Gastroenterological Surgery, EarlyView.
This multicenter study investigated 14 152 minimally invasive esophagectomies (MIEs) using data from the Japanese National Clinical Database and showed a significantly lower operative mortality rate in high‐volume centers than in low‐volume centers. However, no differences in morbidity rates were found between facility sizes.
Taro Oshikiri, Hisateru Tachimori, Hiroaki Miyata, Yoshihiro Kakeji, Ken Shirabe   +4 more
wiley   +1 more source