Results 151 to 160 of about 27,250 (275)

Current landscape and emerging opportunities for using telecytology for rapid on‐site assessment in cytopathology

open access: yesCancer Cytopathology, Volume 133, Issue 7, July 2025.
Abstract In recent years, cytopathology practices increasingly are considering the adoption of digital modalities to support remote rapid on‐site evaluation (ROSE) of fine‐needle aspiration biopsies. Currently, various digital options are available, each of which has unique advantages and limitations.
Savitri Krishnamurthy
wiley   +1 more source

First‐Line Osimertinib for EGFR‐Mutated Squamous Cell Lung Carcinoma: A Case Report

open access: yesCancer Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background Epidermal growth factor receptor (EGFR) mutations in squamous cell lung carcinoma are rare. EGFR‐tyrosine kinase inhibitors are generally less effective for EGFR‐mutated squamous cell lung carcinoma. We herein present a case of EGFR‐mutated squamous cell lung carcinoma that responded to osimertinib.
Yugo Matsumura   +12 more
wiley   +1 more source

First‐in‐Human Single and Multiple Ascending Dose Studies of Balinatunfib, a Small Molecule Inhibitor of TNFR1 Signaling in Healthy Participants

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 1, Page 164-176, July 2025.
Oral small molecule inhibitors of tumor necrosis factor alpha (TNFα) are emerging as attractive therapeutic agents for the treatment of various autoimmune diseases. Balinatunfib (SAR441566), a novel oral inhibitor of tumor necrosis factor receptor 1 (TNFR1) signaling, changes the configuration of the soluble TNFα (sTNFα) trimer and prevents its ...
Nassr Nassr   +12 more
wiley   +1 more source

T‐cell differentiation stage block bias confers hypermethylation and mediastinal preference in T‐cell lymphoblastic lymphoma

open access: yesClinical and Translational Medicine, Volume 15, Issue 7, July 2025.
Malignant T cells in T‐cell lymphoblastic lymphoma (T‐LBL) are predominantly blocked in double negative (DN) and double positive (DP) stages. Block bias induces an immunosuppressive tumour microenvironment (TME) and mediastinal preference. Block bias upregulates UHRF1 leading to hypermethylation of tumour suppressor genes.
Jiali Wang   +10 more
wiley   +1 more source

CORE-BIOPSY OF MEDIASTINAL NEOPLASMS USING A ROBOTIC DEVICE CONTROLLED BY COMPUTER TOMOGRAPHY

open access: bronze
Andrey Andreevich Pustovgar   +3 more
openalex   +1 more source

Current Status of Revisions to the Lugano Classification in Lymphoma

open access: yesHematological Oncology, Volume 43, Issue 4, July 2025.
ABSTRACT In the decade since publication of the Lugano Classification (Cheson et al, J Clin Oncol 2014,32:3059–3068; Barrington et al, J Clin Oncol 2014, 32:3048–3058), major advances in lymphoma therapy and assessment, including metabolic tumor volume (MTV) and circulating tumor DNA (ctDNA) prompted a workshop at the International Conference on ...
The Organizing Committee of the Lugano Classification Workshop
wiley   +1 more source

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