ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost +10 more
wiley +1 more source
Tumor-phrenic nerve spatial relationship and intraoperative traction-induced injury during mediastinal tumor resection: implications for real-time protective strategies. [PDF]
Zhu L +6 more
europepmc +1 more source
Epithelioid hemangioendothelioma - an unexpected diagnosis of a mediastinal tumor with extensive local thrombosis. [PDF]
Liţescu M +6 more
europepmc +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Factors influencing the difficulty of video-assisted thoracoscopic anterior mediastinal tumor resection via the subxiphoid approach. [PDF]
Wei ZY +7 more
europepmc +1 more source
Robot-assisted thoracoscopic resection of a posterior mediastinal tumor with preserving the artery of Adamkiewicz. [PDF]
Nemoto Y +6 more
europepmc +1 more source
ABSTRACT Background This umbrella review summarizes evidence from systematic reviews and meta‐analyses on the efficacy and safety of immune checkpoint inhibitors (ICIs) in hematologic malignancies. To our knowledge, this is the first umbrella review to comprehensively evaluate ICIs across multiple hematologic cancers.
Zhengyu Yu +6 more
wiley +1 more source
The Successful Management of a Life-Threatening Anterior Mediastinal Tumor Using Extracorporeal Membrane Oxygenation and Multidisciplinary Intervention: A Case Report. [PDF]
Fuchigami J +4 more
europepmc +1 more source
Application of the Clamshell Thoracotomy in an Infant with a Large Mediastinal Tumor.
Bendre PS +4 more
europepmc +1 more source
ABSTRACT Introduction The epidemiology of acute leukemia (AL) in children in Afro‐descendant (AD) populations is poorly described, and survival is often considered worse in these populations. The aim of this study is to describe the epidemiology and prognosis of childhood AL in the AD population of the French West Indies/French Guiana (FWI/FG ...
Julie Mascle +16 more
wiley +1 more source

