Results 71 to 80 of about 68,419 (288)

Safe diagnostic management of malignant mediastinal tumors in the presence of respiratory distress: a 10-year experience

BMC Pediatrics, 2020
Background The fundamental treatment for patients with pediatric malignant mediastinal tumors is chemotherapy. Therefore, accurate diagnosis is essential for selecting the appropriate chemotherapeutic regimen.
Tomoko Tanaka, Hizuru Amano, Yujiro Tanaka, Yoshiyuki Takahashi, Tatsuro Tajiri, Takahisa Tainaka, Chiyoe Shirota, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Yukiko Tani, Akinari Hinoki, Hiroo Uchida   +12 more
doaj   +1 more source

Tumor‐Regional Immune Microenvironment: A Critical Factor in the Design of Radiotherapy–Immunotherapy Combination Trials

International Journal of Cancer, EarlyView.
ABSTRACT Clinical trials combining radiotherapy (RT) with immune checkpoint blockade (ICB) have shown improved outcomes in only a fraction of patients, and optimal strategies for integrating these modalities remain under intense investigation. With a few exceptions, phase III combination trials have yielded disappointing results.
Xuanwei Zhang, Hui Wang, Weiyan Tang, Kai Kang, Kateryna Onyshchenko, Taotao Huang, Dan Liu, Jianxin Xue, You Lu, Gabriele Niedermann, Ren Luo   +10 more
wiley   +1 more source

Primary mediastinal seminoma with azoospermia: case report and review of the literature

Frontiers in Oncology
IntroductionSince the first report, primary mediastinal seminoma has a low incidence in the population, and it mainly affects young and middle-aged men, is clinically rare, and accounts for a very small proportion of mediastinal tumors. In this study, we
Zhiwei Li, Qiqi Zhu, Shaorui Niu, Kaibing Xiao, Zhiyang Xiao, Pang Yang   +5 more
doaj   +1 more source

DERMACLEAR: AI‐Powered Insights Into Four Chronic Inflammatory Skin Diseases in Spain

JEADV Clinical Practice, EarlyView.
Using an AI‐enhanced analysis of electronic health records from nearly 50,000 patients, the DERMACLEAR study provides real‐world insights into the prevalence, clinical complexity, comorbidities and treatment patterns of HS, CU, PsO and AD in Spain.
Ana Giménez‐Arnau, Javier Ortiz de Frutos, Raquel Rivera‐Díaz, Lluís Puig, Jaume Notario Rosa, José Luis López‐Estebaranz, Vicente García‐Patos Briones, Ana Martín‐Santiago, José Ignacio Rojo‐Laguna, Elisabet Fernández‐Martínez, Lara Gómez‐Labrador, Esteban Daudén   +11 more
wiley   +1 more source

Myasthenia Gravis and Thymoma

Muscle &Nerve, EarlyView.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor, Lukas Delasos, Daniel P. Raymond, Erik Seroogy, Jason Lempel, Yuebing Li   +5 more
wiley   +1 more source

Diagnostic Yield of EBUS Mediastinal Cryobiopsy Versus TBNA in Suspected Lymphoproliferative Disorders: A Prospective Multicentre Study

Respirology, EarlyView.
We assessed the diagnostic yield of EBUS‐guided transbronchial mediastinal cryobiopsy (EBUS‐TBMC) compared with EBUS‐transbronchial needle aspiration (EBUS‐TBNA) in patients with suspected mediastinal lymphoproliferative disorders (LPDs). EBUS‐TBMC was superior to EBUS‐TBNA and achieved a high diagnostic yield in patients with suspected mediastinal ...
Yaniv Dotan, Ayal Romem, Elad Guber, Michael Kassirer, Daphne Felus, Nimrod Urtreger, Ophir Freund, Hanna A. Dawood, Boaz Tiran, Doron Cohn Shwartz, Sarah Borsekofsky, Amir Bar‐Shai, Evgeni Gershman   +12 more
wiley   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Computed tomography-guided percutaneous needle biopsy for middle mediastinal tumors with retroaortic paravertebral approach: A case report

Radiology Case Reports
A 74-year-old man was referred to our hospital for a close examination of a mediastinal mass. Contrast-enhanced CT showed a middle mediastinal tumor.
Rakuhei Nakama, MD, PhD, Yasunori Arai, MD, Toshihiro Horii, MD, Tatsushi Kobayashi, MD   +3 more
doaj   +1 more source

Cholesterol granuloma mimicking an anterior mediastinal tumor - a case report

, 2020
: There are many different types of mediastinal masses, which makes it challenging to diagnose them. Furthermore, the clinical presentation can range from asymptomatic to life-threatening.
Lauwers, Patrick, Snoeckx, Annemie, Hendrikx, Bart, van Schil, Paul, Broeckx, Glenn   +4 more
core  

Dysphagia Is Associated With Need for Surgical Voice Restoration in Unilateral Vocal Fold Immobility

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To evaluate the association between patient‐reported dysphagia symptoms, measured by the Eating Assessment Tool‐10 (EAT‐10), and the need for surgical voice restoration in patients with unilateral vocal fold immobility (UVFI). Methods A retrospective chart review was conducted on adult patients (≥ 18 years) diagnosed with UVFI at a ...
Julian Purrinos, Eve Bowers, Jackson Rossborough, Ruixan Ma, Dominique Bohorquez, Mursalin M. Anis   +5 more
wiley   +1 more source