Results 111 to 120 of about 86,388 (264)
ABSTRACT Excess adipose tissue has been extensively studied due to its role in the development of chronic diseases and inflammatory conditions. Obesity and visceral adipose tissue (VAT, fat stored within the abdominal cavity and around organs) are associated with increased susceptibility to respiratory infections and chronic low‐grade systemic ...
Rebecca Baumgartner +5 more
wiley +1 more source
Mediastinal Lymphadenopathy in a Child with Kawasaki Disease
Vadood Javadi,1 Reza Shiari,1 Khosro Rahmani,1 Nazanin Farahbakhsh2 1Pediatric Rheumatology Department, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran; 2Pediatric Pulmonology Department, Mofid Children’
Javadi V +3 more
doaj
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle +5 more
wiley +1 more source
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider +4 more
wiley +1 more source
Semen Cryopreservation in Testicular Cancer: Before or After Orchidectomy?
ABSTRACT Background Fertility preservation in patients with testicular cancer remains a clinical priority, yet the optimal timing for sperm cryopreservation—before or after orchidectomy—remains a matter of debate. Objectives The aim of this study was to determine the optimal timing for semen cryopreservation and the best‐quality sample for ART.
Alessandra Buonacquisto +12 more
wiley +1 more source
Causes of Persistent ST Elevation in Patients With Lung Cancer: A Case Report
ST elevation without Q waves in advanced cancer may suggest cardiac metastasis; voltage gradient while repolarization may cause ST elevation in cardiac metastasis. ABSTRACT Cardiac metastases are rare in clinical practice. Herein, we describe the case of a 61‐year‐old male patient who underwent radical left lung cancer surgery > 2 years before the ...
Lijiang Ding, Huayong Jin
wiley +1 more source
Giant atypical lipomatous tumor of the mediastinum
Atypical lipomatous tumors, so-called well differentiated liposarcomas are the intermediate or locally aggressive form of adipocytic tumors. Mediastinum is an uncommon localization for these tumors and they have a potential risk of recurrence following ...
Onder, Sevgen +3 more
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