Results 121 to 130 of about 1,329,491 (311)

Impacts of Rural–Urban Labour Transfer and Land Transfer on Land Efficiency in China: A Analysis of Mediating Effects

Land
In the midst of China’s ongoing rural–urban integration and development, a pivotal transformation involving the realignment of labour dynamics and land utilisation is underway.
Siyi Pei, Sudan Zhao, Xuan Li, Jiahui Li
doaj   +1 more source

Prognosis, Effect Modification, and Mediation [PDF]

European Urology, 2018
Andrew J, Vickers, Gunnar, Steineck
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

SOCIOEMOTIONAL SELECTIVITY (FUTURE TIME PERSPECTIVE, GOAL ORIENTATION) AND SUBJECTIVE WELL BEING [PDF]

, 2011
Successful old age is coveted by every individual who enters late adulthood, which is marked by selfassessment of well-being, known as subjective well-being.
Desiningrum, Dinie Ratri
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The Mediating Effect of Vitamin D on the Association Between Exercise and Triglyceride in Adolescents: A Prospective Cross-sectional Study

Xiehe Yixue Zazhi
ObjectiveTo investigate the mediating role of vitamin D in the association between exerciseand triglyceride among adolescents, as well as its potential molecular mechanisms.MethodsThis prospective cross-sectional study utilized convenience sampling ...
HUANG Bochuan, GUO Xiaoyuan, WANG Yutong, LIU Jiaxuan, PAN Hui, CHEN Shi   +5 more
doaj   +1 more source

PENGARUH GOOD CORPORATE GOVERNANCE DAN LEVERAGE TERHADAP NILAI PERUSAHAAN DENGAN KINERJA KEUANGAN SEBAGAI VARIABEL MEDIASI PADA PERUSAHAAN SUB SEKTOR MAKANAN DAN MINUMAN DI BURSA EFEK INDONESIA [PDF]

This study was conducted with the aim of evaluating the effect of Good Corporate Governance on firm value, with financial performance as a mediating variable.
Ramadhan, Tegar Gilang
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Activities of daily living mediate the association between balance and falls in middle aged and older adults

Scientific Reports
Falls constitute a significant public health issue affecting middle-aged and older adults.The consequences of falls extend beyond physical injuries and compromised quality of life to encompass psychological and socioeconomic dimensions.
Jiaran Jiang, Quan Zhou, Chuanxia Zhang, Keer Cong   +3 more
doaj   +1 more source

The impact of the sports industry on the development of the health industry: an exploration of mediating and threshold effects

Frontiers in Public Health
IntroductionThe sports and health industries play a crucial role in fulfilling individuals' aspirations for an enhanced quality of life and in supporting the development of a Healthy China.MethodsTo explore the impact mechanism of the sports industry ...
Shutong Zhao, Shutong Zhao, Haiyan Huang
doaj   +1 more source