Results 101 to 110 of about 1,329,491 (311)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

More Than Memories? Schema Transference from Media Characters to Real People [PDF]

, 2011
This study focused on whether personality traits and evaluations of television personalities are used to make inferences about new Social interaction partners. It tested the hypothesis that priming schemas of television personalities will bias inferences
Ray, Hilary
core   +2 more sources

Testing high-dimensional mediation effect with arbitrary exposure–mediator coefficients

TEST
In response to the unique challenge created by high-dimensional mediators in mediation analysis, this paper presents a novel procedure for testing the nullity of the mediation effect in the presence of high-dimensional mediators. The procedure incorporates two distinct features.
Yinan Lin, Zijian Guo, Baoluo Sun, Zhenhua Lin   +3 more
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Joint association of sleep duration and depression with new-onset hearing loss: a national cohort study

Frontiers in Nutrition
BackgroundHearing loss, a global health burden, is closely associated with depression and sleep disorders. However, the combined effects of sleep duration and depression on hearing loss risk remain unclear.MethodsData from the China Health and Retirement
Fang Wang, Yu-Jun Xiong, Da-Ming Shao, Tian Lv, Shiqin Chen, Qian-Yuan Zhu   +5 more
doaj   +1 more source

The mediating effect of internal integration on the relationship between supply chain integration and operational performance: Evidence from Moroccan manufacturing companies

Journal of Industrial Engineering and Management, 2019
Purpose: This paper aims to explain the direct effect of supply chain integration on operational performance of manufacturing companies and the mediating effect of internal integration on the relationship between external integration and operational ...
Mohamed Errassafi, Hassan Abbar, Zahra Benabbou   +2 more
doaj   +1 more source

PENGARUH DISIPLIN KERJA TERHADAP KINERJA KARYAWAN DENGAN KEPUASAN KERJA SEBAGAI VARIABEL MEDIASI PADA KARYAWAN CV. EUREEKA INDONESIA [PDF]

This study examines the effect of work discipline on employee performance with job satisfaction as a mediating variable. This research was conducted at CV. Eureeka Indonesia with a sample size of 31 employees.
Sahabuddin, Fuad
core  

Dual Mechanism Mediating Opiate Effects? [PDF]

Science, 1979
S, Amir, R, Blair, P, Shizgal, Z, Amit
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source