Results 91 to 100 of about 648,869 (315)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Results of RUE mediating effect test.

, 2022
Results of RUE mediating effect test.
Fengge Yao (12988315), Lin Li (28817), Shen Zhong (4503439)   +2 more
core   +1 more source

Stress mediates and gender moderates the relationship between cultural intelligence and insomnia symptoms in International students

Scientific Reports
As the number of international students continues to grow globally, insomnia symptoms have become a prominent challenge for this group. Although cultural intelligence (CQ), stress, and gender have often been discussed in relation to sleep health, the ...
Xiang Zhong, Man Luo
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Output of mediating effect.

, 2018
Output of mediating effect.
Sharifah Norul Akmar Syed Zamri (5937899), Hutkemri Zulnaidi (5798324), Riyan Hidayat (5937896)   +2 more
core   +1 more source

The mediating effect of business ties.

, 2022
The mediating effect of business ties.
Xiaozhi Huang (12056729), Xin Cao (288308), Limin Fan (680854), Peng Li (69518)   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The mediating effect of perceived value.

, 2022
The mediating effect of perceived value.
Tian Hewei (13783225)
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The Mediating Role of Spiral of Silence in the Effect of Nomophobia on Social Withdrawal

There is limited research in the literature that examines the relationships between the spiral of silence, nomophobia, and social withdrawal among university students.
Ece Zeybek Yilmaz, Ayhan Bayram
core   +1 more source