Results 71 to 80 of about 648,869 (315)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Effect of mediators on coronary circulation

European Heart Journal, 1991
A number of vasoactive mediators have been identified in plasma and in the heart. Some of them may be liberated in inflammatory heart disease. The action of mediators on coronary vasculature in various animal models and their potential role in inflammatory heart disease is reviewed. Their role in patients remains to be determined.
Ertl, G, Bauer, B, Neubauer, S, Schorb, W, Kochsiek, K   +4 more
openaire   +3 more sources

Test procedure of mediating effect.

, 2022
The 3 test procedure of mediating effect based on Eqs (4)–(6).
Haitao Wu (2411155), Tiecheng Shan (12850481), Xiaodi Qin (12850478)   +2 more
core   +1 more source

Employee Turnover Intention in Aviation Industry

Pakistan Journal of Engineering & Technology, 2022
This empirical study explores the mediation role of organizational embeddedness in the relationship between turnover and quality of work life. The current study investigates how employment variables, such as job satisfaction, organizational commitment ...
Syeda Iqra Musfarat, Rehman Akhtar
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Impact of Smartphone Addiction on Academic Performance of Undergraduates in Sri Lanka: Mediating effect of Technology Driven Multitasking

, 2021
This study aimed to examine university undergraduate’s level of Smartphone Addiction (SA) and to investigate the impact of SA on their Academic Performance (AP) with the mediating effect of Technology-Driven Multitasking behaviour (TDMT).
Praveeni, SMN, Wickramasinghe, CN, S. M. N. Praveeni, C. N. Wickramasinghe   +3 more
core   +1 more source

The long-term mortality burden of childhood traumatic fractures: a mediation analysis of osteoarthritis and psychosocial pathways in older European adults

Archives of Public Health
Propose This study aimed to investigate the long-term associations between childhood hip or femur fractures and the risks of osteoarthritis (OA) and mortality in later life, and to examine the mediating roles of functional limitation, depressive symptoms,
Lan Luo, Songsong Tan, Yunpeng Luo, Meisha Sun, Yangshiqi Li, Yunfen Tian, Guochun Deng, Renyin Yuan, Jianyong Yan, Qian Zhao, Bin Wang, Mazhong Zhang   +11 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Association between eGDR and accelerated aging: the mediating role of ePWV

Diabetology & Metabolic Syndrome
Objective This study examines the association between estimated glucose disposal rate (eGDR) and accelerated aging in middle-aged and older adults, with a focus on the mediating role of estimated pulse wave velocity (ePWV).
Shaoyan Lu, Yu-Jun Xiong, Xiang-Da Meng, Da-Ming Shao, Tian Lv   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source