Results 131 to 140 of about 18,907,323 (361)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Corporate responsibility and financial performance : the role of intangible resources. [PDF]

open access: yes
This paper examines the effects of a firm’s intangible resources in mediating the relationship between corporate responsibility and financial performance.
Surroca, Jordi   +2 more
core  

The mediating effect of green innovation on the relationship between green supply chain management and environmental performance [PDF]

open access: yes, 2019
The emerging environmental awareness of the public, as well as the implementation of governmental regulations, force organisations to employ corporate environmental practices such as green supply chain management (GSCM) and green innovation. Accordingly,
Abbas Mardani   +122 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The human side of leadership: Inspirational leadership effects on follower characteristics and happiness at work (HAW) [PDF]

open access: yes, 2018
Leadership has received significant attention over the past years. Now is the time to refine how leaders impact on followers and their attitudes. This study examines how inspirational leaders influence follower characteristics (FC), and in turn, their ...
Andres Salas Vallina   +2 more
core   +1 more source

Job burnout and turnover intention among Chinese primary healthcare staff: the mediating effect of satisfaction

open access: yesBMJ Open, 2020
Objectives Although China has done a lot in strengthening the primary healthcare system, the high turnover intention is still a social problem to be reckoned with. The objective of this study is to explore the mediating effect of satisfaction between job
Li Ran   +5 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

More Than Memories? Schema Transference from Media Characters to Real People [PDF]

open access: yes, 2011
This study focused on whether personality traits and evaluations of television personalities are used to make inferences about new Social interaction partners. It tested the hypothesis that priming schemas of television personalities will bias inferences
Ray, Hilary
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The Causal Effect of Education on Health [PDF]

open access: yes
We study the contribution of health-related behaviors to the health-education gradient by distinguishing between short-run and long-run mediating effects:while in the former only current or lagged behaviors are taken into account, in the latter we ...
Brunello, Giorgio   +3 more
core  

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