Results 131 to 140 of about 1,318,585 (312)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Prognosis, Effect Modification, and Mediation [PDF]

open access: yesEuropean Urology, 2018
Andrew J, Vickers, Gunnar, Steineck
openaire   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

The Mediating Effect of Vitamin D on the Association Between Exercise and Triglyceride in Adolescents: A Prospective Cross-sectional Study

open access: yesXiehe Yixue Zazhi
ObjectiveTo investigate the mediating role of vitamin D in the association between exerciseand triglyceride among adolescents, as well as its potential molecular mechanisms.MethodsThis prospective cross-sectional study utilized convenience sampling ...
HUANG Bochuan   +5 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Activities of daily living mediate the association between balance and falls in middle aged and older adults

open access: yesScientific Reports
Falls constitute a significant public health issue affecting middle-aged and older adults.The consequences of falls extend beyond physical injuries and compromised quality of life to encompass psychological and socioeconomic dimensions.
Jiaran Jiang   +3 more
doaj   +1 more source

The impact of the sports industry on the development of the health industry: an exploration of mediating and threshold effects

open access: yesFrontiers in Public Health
IntroductionThe sports and health industries play a crucial role in fulfilling individuals' aspirations for an enhanced quality of life and in supporting the development of a Healthy China.MethodsTo explore the impact mechanism of the sports industry ...
Shutong Zhao, Shutong Zhao, Haiyan Huang
doaj   +1 more source

Mediating effect of self-coping mechanisms on associations between financial practices and financial security of female-headed households [PDF]

open access: yes, 2016
Coping process involves contingency actions of individual to alter their cognitive and behaviour to cope with stress encountering events in life. Self-coping mechanisms were examined further as mediating effect between financial practices and financial ...
Abdul Rahim @ Abdul Wahab, Husniyah   +3 more
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

PENGARUH ELECTRONIC WORD OF MOUTH (e-WOM) TERHADAP PURCHASE INTENTION PRODUK KOSMETIK WARDAH DENGAN BRAND IMAGE SEBAGAI VARIABEL MEDIASI (Studi pada Konsumen Produk Kosmetik Wardah di Universitas Muhammadiyah Malang) [PDF]

open access: yes
Usage lectronic word of mouth in consumer communications today helped its emergence purchase intention on certain products, especially in the field of cosmetics for women, brand image existing products also help increase consumer purchasing intentions ...
Kurniawan, Erwin Putra Ragil Wahyu
core  

Home - About - Disclaimer - Privacy