Results 201 to 210 of about 576,017 (266)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Influence of Depressive Symptoms on Disease Activity in Patients with Rheumatoid Arthritis: The Mediating Effect of Self-Efficacy. [PDF]

Medicina (Kaunas)
Lin WW, Yen CT, Huang HL, Livneh H, Lu MC, Chen WJ, Tsai TY.   +6 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

The mediating effect of trust in the physician on the impact of the physician's open communication on patients' adherence to treatment: a cross-sectional study from Turkey. [PDF]

Korean J Med Educ
Kaya RR, Türkmen İ, Ada HE.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The relationship between emotional states and mental well-being in men: mediating effect of leisure-time physical activity. [PDF]

Front Psychol
Güler C, Akkaya CC, Siyahtaş A, Havadar T, Kaya N, Yurtseven CN, Tükenmez A, Duran B.   +7 more
europepmc   +1 more source

The Impact of Empowering Leadership on the Job Crafting of Knowledge Employees: A Moderated Mediating Effect Model. [PDF]

Behav Sci (Basel)
Mao Y, Fang Q, Jiang C, Wu H.
europepmc   +1 more source

The Mediating Effect of Inflammatory Biomarkers in the Associations Between Sarcoidosis and Incident Ischemic Stroke: A Prospective Cohort Study. [PDF]

Brain Behav
Bai Z, Shao W, Huang X, Tan S, Ling Y, Yuan S, Li X, Lyu J.   +7 more
europepmc   +1 more source

The effect of social support on sports performance in high-level collegiate volleyball athletes: the chain mediating effect of emotional intelligence and athletic engagement. [PDF]

Front Psychol
Zhang T, Zhao P, Geng Y, Shi Q, Yang T.
europepmc   +1 more source