Results 251 to 260 of about 1,894,725 (339)

Dnmt3a is an epigenetic mediator of adipose insulin resistance

, 2017
Dongjoo You, Emma Nilsson, Danielle Tenen, Anna Lyubetskaya, James C. Lo, Rencong Jiang, Jasmine Deng, Brian A. Dawes, Allan Vaag, Charlotte Ling, Evan D. Rosen, Sona Kang   +11 more
openalex   +2 more sources

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Compromise, coercion, and delay: best interests decision-making in mediation of paediatric medical treatment disputes. [PDF]

Med Law Rev
Lindsey J, Francis G.
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

B2M regulates ELANE in pyroptosis to affect pancreatic cancer progression. [PDF]

Transl Oncol
Xie H, Hu X, Cai Y, Zhu S, Deng Z.
europepmc   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Epigenetic mediation may explain intergenerational associations between maternal obesogenic lifestyle and children's birth weight: findings from the NorthPop prospective birth cohort. [PDF]

Clin Epigenetics
De Silva K, Lundberg-Ulfsdotter R, Bodén S, Vinnars MT, Ryden P, West CE, Domellöf M, Harlid S.   +7 more
europepmc   +1 more source

Effects of perceived autonomy support from social agents on motivation and engagement of Chinese primary school students: Psychological need satisfaction as mediator

, 2019
Li-Hua Zhou, Nikos Ntoumanis, Cecilie Thøgersen‐Ntoumani   +2 more
openalex   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Establishing Pain Thresholds for Functional Recovery After Lung Cancer Surgery: A Mediation Analysis of the Surgery-Pain-Functioning Causal Pathway. [PDF]

Pain Res Manag
Ma P, Dai W, Li S, Xiang R, Yu H, Wei X, Liao J, Lei C, Xu W, Zhou X, Wang Z, Shi Q.   +11 more
europepmc   +1 more source