Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
The unfairness we feel: How positive and aggressive affect could shape relative deprivation and aggression. [PDF]
BMC PsycholKassab YJ, Halbeisen G, Walther E.
europepmc +1 more source
On the Permissible Range for Parameter used in Inter- mediate-Resonance Treatment [PDF]
, 1968 Yukio ISHIGURO
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MIF as an oncogenic driver of low‐heterogeneity melanomas
Molecular Oncology, EarlyView.Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran +4 more
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Three generations of epigenetic clocks in mediating the adverse effect of smoking on metabolic health. [PDF]
EpigenomicsYeh CY, Lin WY.
europepmc +1 more source
The A-B, B-Cr, A-C mediation paradigm: Recall of A-B following varying numbers of trials of A-C learning [PDF]
, 1967 Ronald H. Hopkins, Rudolph W. Schulz
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Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Dynamic testing with graduated prompts training: Adolescents with executive function deficits. [PDF]
Hong Kong J Occup TherFogel Y.
europepmc +1 more source
Serum-mediated Immune Cellular Responses to Brucella melitensis IV. Infection of Macrophages Under Anaerobic Conditions [PDF]
, 1969 D. J. Ralston, Sanford S. Elberg
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