Results 271 to 280 of about 1,930,794 (341)

Fear of Missing Out and Aggression: Role of Fatigue, Daytime Sleepiness and Self-regulation-A Serial Mediation Model. [PDF]

Ann Neurosci
Ghosal A, Chukkali S, Mukherjee O, Sahni A.   +3 more
europepmc   +1 more source

Late responses to adenoviral-mediated transfer of the aquaporin-1 gene for radiation-induced salivary hypofunction

, 2016
Ilias Alevizos, Changyu Zheng, Ana P. Cotrim, S Liu, Linda McCullagh, Monisha Billings, Corinne M. Goldsmith, Mayank Tandon, Eva J. Helmerhorst, Marcelo A. Catalán, Stamatina Danielides, Paola Pérez, Nikolay P. Nikolov, John A. Chiorini, James E. Melvin, Frank G. Oppenheim, Gabor G. Illei, Bruce J. Baum   +17 more
openalex   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

The impact of physical activity on social anxiety among college students: an analysis of the chain mediation effect of family support and self-efficacy. [PDF]

PeerJ
Yang B, Yang X, Fan Z, Liu C, Zheng Z.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

The influence of sports technology device usage on middle-aged health anxiety: chain mediation effects of health control perception and self-efficacy reconstruction. [PDF]

Front Public Health
Li F, Peng J, Cao L, Zhou D.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Rotating Night Shifts and Physical Well-Being in Nurses: Cross-Sectional Associations Consistent with a Sleep Quality Pathway. [PDF]

Nurs Rep
Kolarić A, Majeed A, Car M, Miskulin I.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Risk factors for spontaneous preterm birth are mediated through changes in cervical length. [PDF]

Commun Med (Lond)
Wolf HM, Romero R, Strauss JF, Tarca AL, Hassan SS, Webb BT, Latendresse SJ, York TP.   +7 more
europepmc   +1 more source