FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Relationship between extraversion and mental health literacy in Chinese adolescents: a chain mediation model. [PDF]
Front PsycholLiu Z, Yuan F, Du J.
europepmc +1 more source
FEBS Open Bio, EarlyView.CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Association of triglyceride and cholesterol with vestibular vertigo: Evidence from univariable and multivariable mendelian randomization and mediation analysis. [PDF]
Braz J OtorhinolaryngolMu Y, Lu Y, Fu W.
europepmc +1 more source
BHMnet: Bayesian high-dimensional mediation analysis with network information integration for correlated mediators. [PDF]
Brief BioinformIm Y, Huang Y.
europepmc +1 more source
Exploring the Impact of Perceived Parental Oversight on Problematic Smartphone Use Among Adolescents in the Digital Age: Database Analysis. [PDF]
JMIR Pediatr ParentHo M, Schulz PJ, Chang A.
europepmc +1 more source
Metabolic pathways linking air pollution to osteoarthritis: Insights from a prospective cohort. [PDF]
PLoS OneZhang B, Li P, Yang C, Fan Z.
europepmc +1 more source
From Trauma to Suicidal Ideation in a Spanish Chronic Pain Population: Cognitive Mediation in the Genesis of Psychological Suffering. [PDF]
J Clin MedMora-Ascó JJ +3 more
europepmc +1 more source