Results 71 to 80 of about 1,930,794 (341)

Exploring Parents’ Everyday Experiences With Digital Media: Barriers and Opportunities for Digital Inclusion

open access: yesMedia and Communication
This article presents qualitative research findings on parents’ digital media practices. Through 32 in-depth interviews with parents of 0–6-year-olds in French-speaking Belgium, the study addresses digital inclusion by exploring the diverse ways parents ...
Caroline Robbeets   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Landscape of Supersymmetric Particle Mass Hierarchies in Deflected Mirage Mediation

open access: yes, 2011
With the aim of uncovering viable regions of parameter space in deflected mirage mediation (DMM) models of supersymmetry breaking, we study the landscape of particle mass hierarchies for the lightest four non-Standard Model states for DMM models and ...
Altunkaynak, Baris   +4 more
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Precontractual Agreements in Selected Legal Systems

open access: yesBaltic Journal of European studies, 2020
Certain legal instruments have been developed in business transactions in order to facilitate the conclusion of an agreement under negotiation. The instruments of this kind are called precontractual agreements.
Sławicki Piotr
doaj   +1 more source

Moving Beyond Brands: Integrating Approaches to Mediation [PDF]

open access: yes, 2013
A briefer version of this article was published in the Alaska Justice Forum: "Moving Beyond Brands: Integrating Approaches to Mediation" by Brian Jarrett. Alaska Justice Forum 29(3–4): 1, 9–12 (Fall 2012/Winter 2013).
Jarrett, Brian
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Reducing Test Bias Through Dynamic Assessment Of Children's Word Learning Ability [PDF]

open access: yes, 2001
This study examined the performance of preschool children from culturally and linguistically diverse backgrounds, both typically developing and with low language ability, on a word-learning task.
Iglesias, Aquiles   +2 more
core   +1 more source

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