Results 71 to 80 of about 1,002,739 (239)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Mediating Climate, Mediating Scale [PDF]
Humanities, 2019 Climate communication is seemingly stuck in a double bind. The problem of global warming requires inherently trans-scalar modes of engagement, encompassing times and spaces that exceed local frames of experience and meaning. Climate media must therefore negotiate representational extremes that risk overwhelming their audience with the immensity of the ...
openaire +2 more sources
Is it time for a global legal framework in Belgium? [PDF]
, 2018 Environmental mediation continues to develop and evolve in different jurisdictions across the world in order to prevent potential environmental conflicts or to resolve the conflicts while avoiding the inherent drawbacks of an adjudicated solution.
Van Hoorick, Geert +2 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Journal of High Energy Physics, 2013 32 pages, 3 figures, references added, minor ...
Baryakhtar, M +2 more
openaire +3 more sources
, 2002 We consider $B_s \to \mu^+ \mu^-$ and the muon $(g-2)_\mu$ in various SUSY breaking mediation mechanisms. If the decay $B_s \to \mu^+ \mu^-$ is observed at Tevatron Run II with a branching ratio larger than $\sim 2 \times 10^{-8} $, the noscale ...
A. Pomarol +13 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Mirage Models Confront the LHC: III. Deflected Mirage Mediation
, 2015 We complete the study of a class of string-motivated effective supergravity theories in which modulus-induced soft supersymmetry breaking is sufficiently suppressed in the observable sector so as to be competitive with anomaly-mediated supersymmetry ...
Everett, Lisa L. +3 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
, 2023 This book has been elaborated in the MediMARE Mediation in Maritime Disputes Project context. MediMARE is a project financed by the EEA Grants (PT - INNOVATION-0065). The project was in place from 19th October 2021 until 30th of September 2023, and was coordinated by the University of Coimbra, through the University of Coimbra Institute for Legal ...
openaire +2 more sources