Results 81 to 90 of about 1,930,794 (341)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Soft Supersymmetry Breaking in KKLT Flux Compactification [PDF]

open access: yes, 2005
We examine the structure of soft supersymmetry breaking terms in KKLT models of flux compactification with low energy supersymmetry. Moduli are stabilized by fluxes and nonperturbative dynamics while a de Sitter vacuum is obtained by adding supersymmetry
Choi, Kiwoon   +3 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

OLD AND NEW RUSSIA. REREADING THE HISTORICAL LEGACY IN LIGHT OF THE WAR IN UKRAINE

open access: yesFilolog
The full-scale invasion of Ukraine by the Russian Federation on February 24th, 2022, brought relations between Russia and the West to an unprecedented breaking point.
Francesca Volpi
doaj   +1 more source

Supporting access to healthcare for refugees and migrants in European countries under particular migratory pressure

open access: yesBMC Health Services Research, 2019
Background In 2015 the increased migratory pressure in Europe posed additional challenges for healthcare providers. The aim of this study was to inform the development of a “Resource Package” to support European Union (EU) member states in improving ...
Antonio Chiarenza   +4 more
doaj   +1 more source

Gauge vs. Gravity mediation in models with anomalous U(1)'s [PDF]

open access: yes, 2008
In an attempt to implement gauge mediation in string theory, we study string effective supergravity models of supersymmetry breaking, containing anomalous gauge factors. We discuss subtleties related to gauge invariance and the stabilization of the Green-
  +37 more
core   +4 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Pratiques et perspectives de gouvernance de l'information au sein des institutions universitaires : cas de l’Institut National de Statistique et d’Economie Appliquée

open access: yesJournal of Information Sciences
Dans un contexte complexe, la gouvernance de l'information (GI) est cruciale. Cette recherche examine ses pratiques, en mettant l'accent sur l'Institut National de Statistique et d’Economie Appliquée (INSEA), la gestion des archives, la protection des ...
Ilham BELKAMEL
doaj   +1 more source

Gaugino-Assisted Anomaly Mediation [PDF]

open access: yes, 2000
We present a model of supersymmetry breaking mediated through a small extra dimension. Standard model matter multiplets and a supersymmetry-breaking (or ``hidden'') sector are confined to opposite four-dimensional boundaries while gauge multiplets live ...
Kaplan, David Elazzar, Kribs, Graham D.
core   +3 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

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