Results 101 to 110 of about 507,043 (295)

Cross-cultural localisation of Serbian tourist destinations' websites: cases of websites of tourism organisations of Belgrade, Novi Sad and Niš [PDF]

open access: yesAnali Ekonomskog fakulteta u Subotici
Tourism and culture are inextricably linked. Visiting another country with a different culture gives tourists the opportunity to gain different perspectives and enjoy the destination as well.
Stojiljković Aleksandra   +1 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Artificial Intelligence at the Service of Digital Archiving: Optimization of Practices and Ethical Challenges

open access: yesJournal of Information Sciences
Digital archiving has undergone a significant evolution in recent years, shifting from a traditional approach to a more computational one. Faced with the explosion of digital data and documents, traditional archiving methods are being overtaken. In this
Nora SAAD   +2 more
doaj   +1 more source

Mediation- the Alternative Processes Lengthy and Expensive [PDF]

open access: yes
Adopt a law on mediation and the mediator profession organization started and the idea that mediation is an important theme of the strategy for justice reform a priority in the Action Plan for implementing the judicial reform strategy 2005-2007.
Bobaru, Daniela
core  

Fictional Characters as Story-Free Denoting Concepts

open access: yesHumanities
Some realist views about fiction are non-objectual in that they see fictional characters not as objects but rather as properties or the like; notably, kinds, roles, or denoting concepts.
Francesco Orilia
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Mediation: Ein Meta-Modell [PDF]

open access: yes, 2004
The Mediation Meta-Model introduced in this article provides a framework for understanding a range of mediation practice models and their relationship to each other and to other ADR processes.
Alexander, N. M., ALEXANDER, Nadja
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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