Results 111 to 120 of about 507,043 (295)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Some Consideration on the Mediation Contract [PDF]
Interaction between people is the most different and diverse, from harmony to the conflict , so that when conflicts arise between them, because they are bound by a contract, the legal system offers a wide range of possibilities for settlement, the ...
Stoica, Veronica
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
MEDIATION OPPORTUNITIES IN CARTEL DAMAGES CLAIMS IN BRAZIL [PDF]
, 2019 The paper discusses the opportunities for the use of mediation in cartel damages claims in Brazil. For this, the paper discusses the growth of the private mediation market in Brazil as well as the art of choosing a consensual dispute resolution method ...
Daniela, Monteiro Gabbay +1 more
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Counterfactual graphical models for longitudinal mediation analysis with unobserved confounding
, 2013 Questions concerning mediated causal effects are of great interest in psychology, cognitive science, medicine, social science, public health, and many other disciplines.
Shpitser, Ilya
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
BMC Public HealthBackground Health mediation practices are multiform—as they constantly adapt to the context—and multilevel, making any study of health mediation complex.
Elodie Richard +11 more
doaj +1 more source
Цифровая социологияThe article is devoted to a sociological analysis of the opinions of family mediation specialists on the problems of spousal negotiability and domestic violence.
O. E. Gracheva, I. V. Mkrtumova
doaj +1 more source