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Mediation analysis methods used in observational research: a scoping review and recommendations
BMC Medical Research Methodology, 2021 Background Mediation analysis methodology underwent many advancements throughout the years, with the most recent and important advancement being the development of causal mediation analysis based on the counterfactual framework.
Judith J. M. Rijnhart +5 more
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Sensitivity Analysis in Nonrandomized Longitudinal Mediation Analysis
Frontiers in Psychology, 2021 Mediation analysis relies on an untestable assumption of the no omitted confounders, which posits that an omitted variable that confounds the relationships between the antecedent, mediator, and outcome variables cannot exist.
Davood Tofighi
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Causal Mediation Analysis with Multiple Mediators [PDF]
Biometrics, 2014 Summary In diverse fields of empirical research—including many in the biological sciences—attempts are made to decompose the effect of an exposure on an outcome into its effects via a number of different pathways. For example, we may wish to separate the effect of heavy alcohol consumption on systolic blood pressure (SBP) into effects ...
Daniel, RM +3 more
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Computational and Structural Biotechnology Journal, 2021 Mediation analysis investigates the intermediate mechanism through which an exposure exerts its influence on the outcome of interest. Mediation analysis is becoming increasingly popular in high-throughput genomics studies where a common goal is to ...
Ping Zeng, Zhonghe Shao, Xiang Zhou
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Generalized Causal Mediation Analysis [PDF]
Biometrics, 2011 The goal of mediation analysis is to assess direct and indirect effects of a treatment or exposure on an outcome. More generally, we may be interested in the context of a causal model as characterized by a directed acyclic graph (DAG), where mediation via a specific path from exposure to outcome may involve an arbitrary number of links (or "stages ...
Albert, Jeffrey M., Nelson, Suchitra
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, 2021 AbstractMediation occurs when a third variable, referred to as a mediator construct, intervenes between two other directly related constructs. More precisely, a change in the exogenous construct results in a change of the mediator construct, which in turn changes the endogenous construct. The mediator analysis evaluates the factors related to the cause–
Joseph F. Hair +5 more
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Flexible Mediation Analysis With Multiple Mediators [PDF]
American Journal of Epidemiology, 2017 The advent of counterfactual-based mediation analysis has triggered enormous progress on how, and under what assumptions, one may disentangle path-specific effects upon combining arbitrary (possibly nonlinear) models for mediator and outcome. However, current developments have largely focused on single mediators because required identification ...
Johan, Steen +3 more
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Priming congruence and COVID-19 vaccination intention: a mediation analysis
Health Psychology Report, 2023 Background This study took place at the height of the fifth wave of COVID-19 in France, coinciding with stigmatizing communication toward the unvaccinated.
Lubomir Lamy +3 more
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Frontiers in Genetics, 2023 Background: High dimensional mediation analysis is frequently conducted to explore the role of epigenetic modifiers between exposure and health outcome.
Fangyao Chen +7 more
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A computational description of simple mediation analysis [PDF]
Tutorials in Quantitative Methods for Psychology, 2018 Simple mediation analysis is an increasingly popular statistical analysis in psychology and in other social sciences. However, there is very few detailed account of the computations within the model.
Caron, Pier-Olivier, Valois, Philippe
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