Results 211 to 220 of about 178,060 (260)

Assessing the Impact of Ambidextrous Leadership on Nurses' Presenteeism: A Latent Profile and Mediation Analysis Study. [PDF]

J Nurs Manag
Zhou X, Yu Y, Yan X.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

How family functioning shapes prenatal bonding: a mediation analysis of depressive symptoms and maternal-fetal attachment. [PDF]

Front Psychiatry
Mammarella S, Giusti L, Camoni L, Mirabella F, Ludovisi M, Roncone R.   +5 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Powerful large scale inference in high dimensional mediation analysis. [PDF]

PLoS Comput Biol
Roy A, Zhang X.
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Gut microbial metabolic disorder in depression: insights from computational modeling and mediation analysis. [PDF]

BMC Microbiol
Zhang Y, Lai W, Wang M, Lai S, Liu Q, Luo Q, Chen Z, Zhao D, Wang Z, Yang F.   +9 more
europepmc   +1 more source

Knowledge, Psychological Distress, and Medication Beliefs Among Tuberculosis Patients in Southwest China: A Mediation Analysis. [PDF]

Healthcare (Basel)
Zheng Y, Dou L, Jike C, Liao R, Yu G, Wang J, Wang R, Wang Y, Bi R, Pei R, Li Y.   +10 more
europepmc   +1 more source

Family support, stigma, and psychological detachment in hemodialysis patients: a cross-sectional mediation analysis. [PDF]

BMC Nephrol
Cong L, Jianyi W, Xiaoran L, Qin W, Nian L, Xianglin L, Lang Y, Li Z, Yongting W, Zuyang X.   +9 more
europepmc   +1 more source