Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Citizen Journalist to Activist: the Language Behind Black Lives Matter [PDF]
This study explores the discourse surrounding an event in the social movement, Black Lives Matter, to gain insights into how digital literacy practices influence and mediate participation in the 21st century civil rights movement for a new generation of ...
Colon, Valeriana
core +1 more source
Framing a Conflict! How Media Report on Earthquake Risks Caused by Gas Drilling: A Longitudinal Analysis Using Machine Learning Techniques of Media Reporting on Gas Drilling from 1990 to 2015 [PDF]
Using a new analytical tool, supervised machine learning (SML), a large number of newspaper articles is analysed to answer the question how newspapers frame the news of public risks, in this case of ...
Klijn, E-H. (Erik-Hans) +2 more
core +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Political scandal at the end of ideology? The mediatized politics of the Bo Xilai case [PDF]
In this article, I use the high-profile Bo Xilai case to illustrate the dialectics of media and politics in contemporary China. I start by explaining some of the similarities and key differences between mediatized politics in the West and in China.
Meng, Bingchun
core +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Games without Frontiers: A Framework for Analyzing Digital Game Cultures Comparatively
Currently in game studies there is a gap in frameworks for comparatively researching game cultures. This is a serious shortcoming as it ignores the transcultural and transnational aspects of games, play and their cultures.
Ahmed Elmezeny, Jeffrey Wimmer
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Public Managers, Media Influence, and Governance: Three Research Traditions Empirically Explored [PDF]
Nowadays, media and media logic have become important and inherent elements in everyday practices of public administration and policy making. However, the logic of the media is often very different from, and conflicting with, the logic of political and ...
Altheide D. L. +16 more
core +1 more source

