Results 111 to 120 of about 1,219,522 (300)
Mediation and Conflict Management [PDF]
Mediation is a popular process to manage conflicts, but there is little systematic insight into its mechanisms. This paper discusses the results from an experiment in which a mediator can induce two conflict parties to behave cooperatively.
Gerald Eisenkopf
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Современное состояние и пути совершенствования медиации в уголовном судопроизводстве Кыргызской Республики [PDF]
Пенитенциарная наукаВведение: в настоящее время доказано, что использование медиативных процедур в различных сферах общественной жизни, как правило, характеризуется высокой степенью эффективности разрешения конфликтов.
Анисимов, В.Ф. +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Revista Transilvană de Ştiinţe Administrative, 2012 The study researches the existing mediator professions in public administration (sanitary mediator, school mediator, social mediator) by means of comparative analysis with the mediator profession regulated by Law no.
Emilia Lucia CĂTANĂ
doaj
On Partial Identification of the Pure Direct Effect [PDF]
, 2015 In causal mediation analysis, nonparametric identification of the pure (natural) direct effect typically relies on, in addition to no unobserved pre-exposure confounding, fundamental assumptions of (i) so-called "cross-world-counterfactuals" independence
Kanki, Phyllis +3 more
core +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Mapping Perspectives on the EU as Mediator [PDF]
, 2015 Research on the European Union’s role as a meditator is nascent. It predominantly focuses on case studies or is cursorily embedded within wider research on the European Union (EU) as a crisis manager. Moreover, there is a significant disconnect between
Haastrup, Toni
core
Galactic Center Excess in Gamma Rays from Annihilation of Self-Interacting Dark Matter
, 2015 Observations by the Fermi-LAT telescope have uncovered a significant $\gamma$-ray excess toward the Milky Way Galactic Center. There has been no detection of a similar signal in the direction of the Milky Way dwarf spheroidal galaxies.
Kaplinghat, Manoj +2 more
core +1 more source