Results 91 to 100 of about 1,219,522 (300)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Appropriation of Information, Knowledge Construction and the Role of Mediator
Revista Interamericana de Bibliotecología, 2018 Knowledge construction is a complex process in which the widespread use of the term information is not, by itself, sufficient to cover its nuances. This leads to a host of discussions of the importance of appropriation of information, which is a key ...
Heloá Cristina Oliveira-DelMassa +1 more
doaj +1 more source
Mediating Climate, Mediating Scale [PDF]
Humanities, 2019 Climate communication is seemingly stuck in a double bind. The problem of global warming requires inherently trans-scalar modes of engagement, encompassing times and spaces that exceed local frames of experience and meaning. Climate media must therefore negotiate representational extremes that risk overwhelming their audience with the immensity of the ...
openaire +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Frontiers in Pain ResearchBackgroundLittle is known about whether the recommended, non-pharmacological treatments for chronic pain yield reductions in healthcare utilization, social costs and increased productivity in actual practice.MethodsThe primary aim of this study (n = 232)
Sophia Åkerblom +5 more
doaj +1 more source
Journal of High Energy Physics, 2013 32 pages, 3 figures, references added, minor ...
Baryakhtar, M +2 more
openaire +3 more sources
Exploring Bosonic Mediator of Interaction at BESIII
, 2019 We present a comprehensive investigation on the possibility of the search for new force mediator $X$ boson in $e^+e^-$ collision and $J/\psi$ decay at the BESIII experiment.
Jiang, Jun, Qiao, Cong-Feng, Yang, Hao
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Frontiers in EndocrinologyBackgroundOsteoporotic fractures (OPFs) are a major global health concern, affecting nearly 200 million individuals worldwide. Notably, patients with type 2 diabetes mellitus (T2DM) face a heightened fracture risk, even when bone mineral density (BMD) is
Jia-qi Liang +12 more
doaj +1 more source