Results 241 to 250 of about 5,004,571 (383)

Plasminogen Activator Inhibitor-1 Is a Marker and a Mediator of Senescence.

Arteriosclerosis, Thrombosis and Vascular Biology, 2017
D. Vaughan, R. Rai, S. Khan, M. Eren, A. Ghosh   +4 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The distinct contribution of sternotomy to the systemic inflammatory response during children's heart surgery. [PDF]

Front Immunol
Bierer JD, Paffile J, Stanzel R, Henderson M, Sapp J, Andreou P, Marshall JS, Horne D.   +7 more
europepmc   +1 more source

Tanshinone IIA Restrains Hepatocellular Carcinoma Progression by Regulating METTL3-Mediated m6A Modification of TRIB3 mRNA

Ying Jiang, Xinjie Wang, Zhenyang Wang, Shengliang Zhang, Jianhua Wang, Xianglong Wang, Yang Zhang   +6 more
openalex   +1 more source

Mediation architecture of personal robot applications based on a communications model

, 2005
Akihiro Kobayashi
openalex   +2 more sources

Author response for "Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunity"

, 2020
Matthijs J.D. Baars, Thera Douma, Dimitre R. Simeonov, Darienne R. Myers, Kayla Kulhanek, Saikat Banerjee, Susan Zwakenberg, Marijke Baltissen, Mojtaba Amini, Sytze de Roock, Femke van Wijk, Michiel Vermeulen, Alexander Marson, Jeroen P. Roose, Yvonne Vercoulen   +14 more
openalex   +1 more source

ENHANCED CERULOPLASMIN MEDIATES TUMOR ANGIOGENESIS IN LUNG CANCER [PDF]

, 2019

openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Analyzing multiple mediators in multiple single-mediator models leads to wrong conclusions. [PDF]

Proc Natl Acad Sci U S A
Loh WW.
europepmc   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source