Results 91 to 100 of about 16,514,941 (283)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Indian Journal of Community MedicineBackground: Internet addiction has become a very common disorder because of which youngsters are wasting a lot of time, becoming irritable and depressed and having poor academic/ work performance and are becoming victims of social isolation.
Smita M Nimbannavar
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Indian Journal of Community MedicineBackground: Smartphones have become an indispensable necessity for medical students because of their various demands and comforts. The excessive use of smartphones may lead to addiction which can negatively affect physical and mental health including ...
Indu Dinesh, K S Ravish, T S Ranganath
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Resolving Medical Disputes: Lessons from U.S. Arbitration for Indonesia’s Legal Framework
Hasanuddin Law ReviewArbitration serves as a dispute resolution method that offers notable benefits, especially in cases related to medical issues. In contrast, other methods such as litigation are often seen as less effective, while mediation lacks executory power due to ...
Muhammad Fakih +4 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Amygdalin as a Potential Anti-Cancer Agent: A Concise Review of Therapeutic Insights and Mechanisms
Baghdad Journal of Biochemistry and Applied Biological SciencesAmygdalin, also known as laetrile, has generated significant controversy within the scientific medical community regarding its efficacy as a cancer treatment. Extracted primarily from the seeds of fruits like apricots and almonds, it has been promoted by
Raghad F. Al-Ansari +5 more
doaj +1 more source