Results 141 to 150 of about 13,122,907 (389)

MEDICAL REVIEW. [PDF]

open access: yesThe Lancet
Any copyright on this work is most likely expired, given life expectancy and copyright duration at the time of publication, or when rolling copyright occurred (i.e., changes to the legislation extending the copyright term). In case of a takedown request, the depositor requests to be provided with legal documentation from the person/organization ...
openaire   +5 more sources

Medical libraries and medical research

open access: yesAcademic Medicine, 1966
Presented at the Billings Centennial at the National Library of Medicine in Bethesda, MD. Fogarty reminded his audience of Billings' role in early federal support of research as well as in the growth of the Surgeon General's Library, and then discussed the urgent need for better medical library systems that could keep the growing volume of ...
openaire   +4 more sources

Medical Education and Medical Reform [PDF]

open access: yes, 1995
Au XIX e siecle, l'enseignement medical a subi quelques reformes afin de centrer davantage l'enseignement a l ...
openaire   +3 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Importance of practical surgical training in increasing knowledge and skills in surgical fields among medical students on the example of the First National Polish Surgical Summerschool

open access: yesJournal of Education, Health and Sport, 2017
Medical students often choose surgical disciplines for their dream career. Surgery, which is both science and art, requires not only theoretical but also essential practical training, necessary in the correct surgical technique and consequently lower ...
Maria Golebiowska   +4 more
doaj  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

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