Results 171 to 180 of about 13,122,907 (389)

Ontology of Bio-Medical Educational Objectives (OBEO): ein Vorschlag für eine Ontologie medizinischer Lernziele / A proposal for an Ontology of Bio-Medical Educational Objectives (OBEO)

open access: yesGMS Medizinische Informatik, Biometrie und Epidemiologie, 2010
Objectives: The Ontology of Bio-Medical Educational Objectives (OBEO) is a formal ontology for the annotation of educational objective catalogues and learning object resources to improve their usability. OBEO has been designed to allow semantic retrieval
Boeker, Martin   +3 more
doaj  

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

MEDICAL PIONEER, AERONAUTS [PDF]

open access: green, 1919
F. J. Poynton
openalex   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

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