Results 71 to 80 of about 17,146,537 (313)
Mona Makita,1,* Miyu Onishi,1,* Chika Kouno,1 Rika Kawabe,1 Naoki Doi,1 Yukinobu Tahu,2 Tomoki Aoyama,1 Momoko Nagai-Tanima1 1Department of Human Health Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan; 2Kyoto ...
Makita M +7 more
doaj
Prescribing Frequent Haemodialysis in Complex Patients: Highlights from the 55th ERA–EDTA Congress
At the 55th European Renal Association–European Dialysis and Transplant Association (ERA–EDTA) Congress in Copenhagen, Denmark, physicians from the USA, UK, and France presented an educational symposium entitled ‘Complex Patients May Be Better Treated ...
NxStage Medical
doaj
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Iñigo Ojanguren,1– 3 Francisco Ramos-Lima,4 Gabriel Niza,4 José Julio Herrero,4 Marta Alegría,4 Gema Monteagudo,4 Manuel J Rial3,5,6 1Respiratory Department, Hospital Universitari Vall d’Hebron, Departament de Medicina, Universitat Autònoma de Barcelona (
Ojanguren I +6 more
doaj
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
MedFusionGAN: multimodal medical image fusion using an unsupervised deep generative adversarial network [PDF]
Mojtaba Safari +2 more
openalex +1 more source
Campus Update: December 1992 v. 4, no. 10 [PDF]
Monthly newsletter of the BU Medical ...
Boston University Medical Center
core
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
The Other Side of Medicalization: Self-Medicalization and Self-Medication [PDF]
The concept of medicalization has given rise to considerable discussion in the social sciences, focusing especially on the extension of medicine's jurisdiction and its hold over our bodies through the reduction of social phenomena to individual biological pathologies.
openaire +3 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

