Results 71 to 80 of about 17,146,537 (313)

Changes in Knowledge and Compliance with Pitch Count Recommendations Among Youth Baseball Coaches: A Cross-Sectional Comparison at Two Time Points

open access: yesOpen Access Journal of Sports Medicine
Mona Makita,1,* Miyu Onishi,1,* Chika Kouno,1 Rika Kawabe,1 Naoki Doi,1 Yukinobu Tahu,2 Tomoki Aoyama,1 Momoko Nagai-Tanima1 1Department of Human Health Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan; 2Kyoto ...
Makita M   +7 more
doaj  

Prescribing Frequent Haemodialysis in Complex Patients: Highlights from the 55th ERA–EDTA Congress

open access: yesEuropean Medical Journal Nephrology, 2018
At the 55th European Renal Association–European Dialysis and Transplant Association (ERA–EDTA) Congress in Copenhagen, Denmark, physicians from the USA, UK, and France presented an educational symposium entitled ‘Complex Patients May Be Better Treated ...
NxStage Medical
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Evolution of Disease Burden in Severe Asthma Patients by Biological Treatment Status: Interim Analysis of the BREATHE Study

open access: yesJournal of Asthma and Allergy
Iñigo Ojanguren,1– 3 Francisco Ramos-Lima,4 Gabriel Niza,4 José Julio Herrero,4 Marta Alegría,4 Gema Monteagudo,4 Manuel J Rial3,5,6 1Respiratory Department, Hospital Universitari Vall d’Hebron, Departament de Medicina, Universitat Autònoma de Barcelona (
Ojanguren I   +6 more
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Campus Update: December 1992 v. 4, no. 10 [PDF]

open access: yes, 1992
Monthly newsletter of the BU Medical ...
Boston University Medical Center
core  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The Other Side of Medicalization: Self-Medicalization and Self-Medication [PDF]

open access: yesCulture, Medicine, and Psychiatry, 2013
The concept of medicalization has given rise to considerable discussion in the social sciences, focusing especially on the extension of medicine's jurisdiction and its hold over our bodies through the reduction of social phenomena to individual biological pathologies.
openaire   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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