Mining multi-center heterogeneous medical data with distributed synthetic learning [PDF]
, 2023 Qi Chang +10 more
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Sex and Gender Driven Modifiers of Alzheimer’s: The Role for Estrogenic Control Across Age, Race, Medical, and Lifestyle Risks [PDF]
, 2019 Aneela Rahman +9 more
openalex +1 more source
Long-term risk factors for suicide in suicide attempters examined at a medical emergency in patient unit: results from a 32-year follow-up study [PDF]
, 2020 Sara Probert-Lindström +4 more
openalex +1 more source
The Influence of Self-Esteem and Psychological Flexibility on Medical College Students' Mental Health: A Cross-Sectional Study [PDF]
, 2022 Jiamei Guo +8 more
openalex +1 more source
The Relationship between Perfectionism with Burnout through Academic Engagement [PDF]
Pizhūhish dar Āmūzish-i ̒ulūm-i Pizishkī, 2017 introduction: Today, researchers identified medical students susceptible to burnout that it not only leads to undesirable outcome such as failed, conditional pass, unsuccessful in acquiring necessary specialty even deportation but also, losing physical ...
MH Seif, A Rastgar, R Ershaddi
doaj
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Translating the Diabetes Prevention Program Into an Urban Medically Underserved Community [PDF]
, 2008 Miriam Seidel +4 more
openalex +1 more source
Study of research self-efficacy components among postgraduate students in Shahrekord University of Medical Sciences [PDF]
Pizhūhish dar Āmūzish-i ̒ulūm-i Pizishkī, 2017 Introduction: SelfSelf-efficacy refers to the degree of one's control over his/her ability to perform certain activities. Students' research self-efficacy represents their confidence in their own ability to conduct various research activities. This study
A Kazemi-Vardanjani +2 more
doaj
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source