Results 61 to 70 of about 286,940 (298)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Reproductive justice: A framework for abortion law reform [PDF]

open access: yes, 2018
Australia has seen a number of efforts at reform of abortion laws in recent years. Some jurisdictions have decriminalised abortion entirely, and other states have made efforts to reform abortion law without complete decriminalisation. At the other end of
Galloway, Kathrine, McGrath, Jemima
core   +2 more sources

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

open access: yesAdvanced Science, EarlyView.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He   +18 more
wiley   +1 more source

Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes

open access: yesAdvanced Science, EarlyView.
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang   +8 more
wiley   +1 more source

The Effects of Legalized Abortion in England [PDF]

open access: yes, 1971
Dr. O\u27Sullivan traces the process leading to the passage of the 1968 British Abortion Act and the consequences of that act with a view to helping the American medical profession learn from the British experience. This article discusses the effect that
O\u27Sullivan, J. Vincent
core   +1 more source

From Multiple Congenital Anomalies to Pituitary Gland Malformation: Wide Spectrum of Clinical Features in a Family With FOXA2 Variant

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT FOXA2 (hepatocyte nuclear factor‐3β, HNF‐3β) encodes a transcriptional activator involved in early embryogenesis, particularly in the patterning and differentiation of midline structures such as the neural tube, foregut, and pituitary gland. Its role in human pathogenesis was first suspected when patients with deletion of chromosome 20p11.2 ...
Christopher Connolly   +3 more
wiley   +1 more source

Abortion care in women with underlying medical conditions: The role of multidisciplinary team approach in increasing safety of abortion procedures

open access: yesPublic Health Challenges, 2023
Background There are no clear data driving most clinical recommendations for abortion care in women with underlying medical conditions, such as cardiac disease.
Abraham Fessehaye Sium   +4 more
doaj   +1 more source

The Novel ACTC1 p.Gly50Ser Variant Is Associated With Arrhythmia and Secondary Features of HCM Without Hypertrophy

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The key diagnostic criterion for hypertrophic cardiomyopathy is the presence of otherwise unexplained hypertrophy. Current definitions of HCM rely on specific thresholds to establish a diagnosis, while guideline directed risk stratification algorithms take its magnitude into consideration.
Thomas D. Gossios   +9 more
wiley   +1 more source

Gambaran Karakteristik Kejadian Abortus Di Rumah Sakit Umum Umi Barokah Boyolali [PDF]

open access: yes, 2018
Maternal mortality 15-50% caused by abortion. Abortion can result indeath from continuous bleeding and infection during abortion. Some of the factorsthat predispose to abortion include fetal factors, maternal factors, environmental factors, age, parity,
, Dr. Faizah Betty Rahayuningsih, S.Kep., M.Kes.   +1 more
core  

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12‐Related Developmental Disorders

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy