Results 91 to 100 of about 2,335,008 (261)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Tidal volume and mortality during extracorporeal membrane oxygenation for acute respiratory distress syndrome: a multicenter observational cohort study

Annals of Intensive Care
Background: Approximately half of the patients with acute respiratory distress syndrome (ARDS) receiving extracorporeal membrane oxygenation (ECMO) remain ECMO-dependent beyond 14 days after ECMO initiation.
Torben M. Rixecker, Jeannine L. Kühnle, Johannes Herrmann, Christopher Lotz, Christian Kühn, Frederik Seiler, Carlos Metz, Armin Kalenka, Oxana Mazuru, Kai Borchardt, Ralf M. Muellenbach, Robert Bals, Matthieu Schmidt, Patrick Meybohm, Vitalie Mazuru, Philipp M. Lepper, Janno Schade, Noah Paschke, Martha E. Hübsch, Quirin Notz, Daniel Röder, Peter Kranke, Michaela L. Merten, Micha Landoll, Peter Spieth, Stefan Kluge, Dominik Jarczak, Kevin Roedl, Michael Sonntagbauer, Christian Putensen, Jens-Christian Schewe, Stefan F. Ehrentraut, Stefan Kreyer, Andreas Wehrfritz, Ixchel Castellanos, Karl Bihlmaier, Karsten Schmidt, Thorsten Brenner, Frank Herbstreit, Florian Espeter, Jan Wiefhoff, Richard K. Ellerkmann, Daniel Oswald, Björn Ellger, Gösta Lotz, Florian J. Raimann, Tobias Wengenmayer, Dawid L. Staudacher, Viviane Zotzmann, Onnen Moerer, Matthias Kochanek, Patricia Glaser, Falk Fichtner, Marc Bodenstein, Michael Findeisen, Vanessa Rembold, Markus Heim, Gerhard Schneider, Tobias Lahmer, Jan-Sören Padberg, Carsten Hullermann, Andre P. Becker, Carlos Metz, Peter Rosenberger, Valbona Mirakaj, Alice-Marie Bernard, Stephan Braune, Rebecca Roth, Anna Grau, Peter Heuschmann, Christian Karagiannidis   +70 more
doaj   +1 more source

The educational use of social networking sites among medical and health sciences students: a cross campus interventional study. [PDF]

BMC Med Educ, 2022
Dash NR, Hasswan AA, Dias JM, Abdullah N, Eladl MA, Khalaf K, Farooq A, Guraya SY.   +7 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Awareness, knowledge and practices related to intra-abdominal hypertension and abdominal compartment syndrome among intensive care providers: a systematic scoping review

Annals of Intensive Care
Objectives: To provide a comprehensive overview of current research on intensive care providers’ awareness, knowledge, and practices regarding IAP/IAH/ACS, as well as barriers to IAP measurement.
ZhiRu Li, FangYan Lu, JingYun Wu, YanHong Dai, Yan Wang, Li Zheng, HuaFen Wang   +6 more
doaj   +1 more source

Satisfaction with online learning in the new normal: perspective of students and faculty at medical and health sciences colleges. [PDF]

Med Educ Online, 2021
Elshami W, Taha MH, Abuzaid M, Saravanan C, Al Kawas S, Abdalla ME.   +5 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Population-wise incidence and outcomes of patients requiring invasive and non-invasive mechanical ventilation in China: a nationwide retrospective analysis by age, sex, and comorbidity

Annals of Intensive Care
Background: Mechanical ventilation is a critical yet labor-intensive medical resource with limited availability. However, population-based data on its utilization and outcomes remain scarce in China.
Maomao Cao, Rong Liufu, Boyang Wang, Wei Pan, Hongda Chen, Longxiang Su, Yun Long, Xiang Zhou, Li Weng, Bin Du   +9 more
doaj   +1 more source

Bibliometric profile of the African Academy of Sciences medical and health sciences fellows. [PDF]

Pan Afr Med J, 2021
Balogun J, Mamuzo E, Okonofua F, Balogun A, Oyeyemi A.   +4 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source