Results 81 to 90 of about 2,335,008 (261)

Development of a gene panel for immune status assessment in sepsis

open access: yesAnnals of Intensive Care
Background: Sepsis is characterized by a dysregulated immune response to infection, with a balance between hyperinflammation and immunosuppression, which determines the patient's immune status.
Chao Gao   +12 more
doaj   +1 more source

Advances in medical and health sciences

open access: yesAdvances in Biomedical and Health Sciences, 2022
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

IFNγ in human sepsis: a scoping review

open access: yesAnnals of Intensive Care
Background: The cytokine IFNγ is released primarily by lymphocytes to initiate and orchestrate immune responses in a broad range of target cells. Whereas immune cells release inflammatory mediators and initiate antimicrobial responses when stimulated by ...
Daniel Thomas-Rüddel   +43 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Bereavement interventions for families in the ICU: a scoping review informed by a core outcome set

open access: yesAnnals of Intensive Care
Background: Families confronting the death of a loved one in the intensive care unit (ICU) are at greater risk of experiencing complicated grief than families bereaved in other circumstances.
Sarah Foran   +8 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A predictive model for early intubation in patients with COVID–19–induced acute hypoxemic respiratory failure under awake prone position

open access: yesAnnals of Intensive Care
Background: Awake prone positioning (APP) reduces the risk of endotracheal intubation and mortality in COVID–19–related acute respiratory failure (ARF) receiving high–flow nasal oxygen (HFNO).
Luis Morales–Quinteros   +10 more
doaj   +1 more source

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