Results 211 to 220 of about 4,230,555 (387)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Evaluating Interprofessional Education Readiness and Perceptions Among Health Professions Students

open access: yesAdvances in Medical Education and Practice
Nouf Sulaiman Alharbi,1– 3 Nourah Mohammed Alenazi,4 Alaa Althubaiti,2,5 Reem Alkahtani,2,3,6 Seema Nasser,2,3,7 Marwh Gassim Aldriwesh2,3,8 1Department of Medical Education, College of Medicine, King Saud bin Abdulaziz University for Health Sciences ...
Alharbi NS   +5 more
doaj  

Clinical and Translational Research Capacity Building Needs in Minority Medical and Health Science Hispanic Institutions [PDF]

open access: hybrid, 2014
Estela S. Estapé‐Garrastazu   +5 more
openalex   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee   +9 more
wiley   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Assessment of Hospital Emergency Response Against Disasters Hospitals Of Iran University of Medical Siences: 2017

open access: yesپژوهش‌های سلامت‌محور, 2018
Assessment of Emergency Response of Teaching Hospitals Affiliated to Iran University of Medical Silences against Disasters   Seyedin Seyed Hesam1, Hasanpoor Edris2, Hasanzadeh Ebrahim3, Sheikhy-Chaman Mohammadreza4*   1.
Seyed Hesam Seyedin   +3 more
doaj  

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