Results 91 to 100 of about 1,175,529 (305)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Dynamics of career attractiveness and preferences among Swiss medical students: an observational study at the end of the master’s program

Medical Education Online
Medical career preferences are in focus because the future medical workforce should align with society’s needs. The study investigated how medical students’ perceptions of the attractiveness of various clinical and non-clinical career options evolved as ...
Stefania Di Gangi, Markus Inauen, Stefan Markun, Oliver Senn   +3 more
doaj   +1 more source

Witnessing history: a personal view of half a century in public health [PDF]

, 2018
Former Chief Medical Officer Sir Kenneth Calman recently celebrated 50 years in medicine. It was a period which saw the evolution of the public health agenda from communicable diseases to diseases of lifestyle, the change from a hospital-orientated ...
Bergman, B.P., Calman, K.C., Chandler, A.S., Laing, F.   +3 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Determinan Pilihan Karir Mahasiswa Fakultas Kedokteran sebagai Spesialis di Indonesia

Jurnal Pendidikan Kedokteran Indonesia, 2014
Background: In this “Jaminan Kesehatan Nasional” (JKN) era, career preference among medical students became an important issue to be concerned with, especially regarding career as a specialist physician in order to ensure equal distribution of doctor's ...
Rizma Adlia Syakurah, Dwi Atika Sari, Dendy Riansyah, Priska Yolanda   +3 more
doaj   +1 more source

Factors affecting medical students in formulating their specialty preferences in Jordan [PDF]

, 2008
Background In recent years there has been a growing appreciation of the issues of career preference in medicine as it may affect student learning and academic performance.
Yousef Khader, Dema Al-Zoubi, Zouhair Amarin, Ahmad Alkafagei, Mohammad Khasawneh, Samar Burgan, Khalid El Salem, Mousa Omari, B Wright, IC McManus, R Hutt, PB Zeldow, P Saigal, A Pawełczyk, J Paris, H Crimlisk, ER Dorsey, D Feifel, PE Reeve, J Parkhouse, T Lambert, A Mariolis, ED Avgerinos, EA Egerton, JH McCord, PA Pugno, JH Senf, LR Millan, JH Burack, B Buddeberg-Fischer, DM Ambrozy, MC Henderson, B Starfield   +32 more
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Building a comprehensive mentoring academy for schools of health. [PDF]

, 2019
Formal mentoring programs are increasingly recognized as critical for faculty career development. We describe a mentoring academy (MA) developed for faculty across tracks (i.e., researchers, clinicians, educators) within a "school of health" encompassing
Giacinto, Rebeca E, Meyers, Frederick J, Rainwater, Julie A, Sauder, Candice AM, Schweitzer, Julie B, Ton, Hendry   +5 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source