Results 91 to 100 of about 289,351 (302)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Medical office professionals: a practical career guide Practical career guides./ Marcia Santore.

open access: yes, 2019
WlAbNL Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).Includes bibliographical references and index.Medical Office Professionals ...
Santore Marcia
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

The future of medical careers [PDF]

open access: yesMedical Journal of Australia, 2014
Scott, A, Joyce, CM
openaire   +3 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Men in non-traditional occupations: Career entry, career orientation and experience of role strain

open access: yes, 2006
This paper sets out to explore the experiences of men in non-traditional occupations. In particular it focuses on the dynamics of career entry, career orientation (i.e. preference for intrinsic or extrinsic rewards) and the possible existence, nature and
Simpson, R
core  

Current Issues and Future Considerations in Undergraduate Medical Education from the Perspective of the Korean Medical Doctor Development System

open access: yes, 2018
Observation of the current Korean medical education and training system shows that certain negative traits of unchangeable solidification engraft themselves so deeply into the overarching system that they are now hampering the state of the national ...
연세대학교 의과대학
core   +1 more source

Medical Student Career Choice’s Determinants: A Qualitative Study

open access: yesGlobal Medical & Health Communication, 2017
Choosing a career is an essential stage in medical students’ life. Previous researchers all across the world have been conducted studies to examine determinants of career choices in general and medical careers in sociodemographic and behavioral ...
Rizma Adlia Syakurah   +3 more
doaj  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Who needs mentoring program among medical students

open access: yes, 2008
Purpose & Method : To describe medical students need on the mentoring program and relationship with career choice, 186/251 (74 .1 %) of first-and second-year medical students at Yonsei University College of Medicine, Seoul, Korea were surveyed.
연세대학교 의과대학
core  

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