Results 61 to 70 of about 6,488,174 (302)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Root Cause Analysis of the Influencing Factors of Professional Identity in Rural Order-oriented Medical Students: a Qualitative Research [PDF]

Zhongguo quanke yixue
Background With the continuous development of the training program of rural order-oriented medical students (referred to as publicly-funded medical students) in China, the talent team of general practice is constantly enriched, and the professional ...
QIAO Xue, YIN Yongtian, LUO Wenjun, LI Yinghui, YANG Jinguang, LI Jingwei, CHEN Hongzhi
doaj   +1 more source

Anatomical Variations of Upper Segmental Renal Artery and Clinical Significance [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: Classically each kidney is supplied by a single renal artery. In its course renal artery divides into anterior and posterior division, both of these division further divide into segmental arteries that are apical, upper, middle, lower ...
GYAN PRAKASH MISHRA, SHOBHA BHATNAGAR, BRIJENDRA SINGH   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Understanding the USMLE journey of Brazilian medical students and graduates: a narrative review

Frontiers in Medicine
Over the past decades, advances in medical technology and research have promoted the globalization of medicine, drawing medical students and physicians worldwide into seeking for better career and financial prospects, as well as enhanced clinical and ...
Beatriz S. Garcia-Rosa, Beatriz S. Garcia-Rosa, Lucas G. Urmenyi, Lucas G. Urmenyi, Gabriel C. Santana, Gabriel C. Santana, João Vitor M. Marques, Joao P. Miguez-Pinto, Joao P. Miguez-Pinto, Joao P. Miguez-Pinto, Clara Ramalho, Daniel Boczar, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade   +15 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Perfiles de calificaciones obtenidas por estudiantes de medicina en la asignatura Salud Pública durante los cursos académicos desde 2005 hasta 2008 Profiles of grades obtained by medical students in the subject Public Health during the academic years from 2005 to 2008

Medisan, 2013
Introducción: En el sistema de educación médica superior cubano, la evaluación del aprendizaje implica el control y la valoración de los conocimientos, las habilidades y los hábitos, además de los modos de actuación que los estudiantes van adquiriendo a ...
Luis Eugenio Valdés García, Yadira Durán Álvarez, Xiomara Amiot Reyes   +2 more
doaj  

RECOGNITION OF A GREAT MEDICAL CAREER [PDF]

Journal of the American Medical Association, 1920
To the Editor: —In our country there are few formal means for recognizing in any public way the services of a great physician or a great teacher. In the older countries such services have been recognized by the bestowal of honors, or nobility or grants of money, or by other official means which call attention to the services rendered.
openaire   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source