Results 71 to 80 of about 2,415,362 (310)

Health Savings Accounts and High-Deductible Health Insurance Plans: Implications for Those With High Medical Costs, Low Incomes, and the Uninsured [PDF]

, 2009
Considers the advantages and disadvantages of health savings accounts and high-deductible health plans, including implications for people with high medical needs and for efforts to contain healthcare costs.
Linda J. Blumberg, Lisa Clemans-Cope
core  

Cost-effectiveness of left ventricular assist devices (LVADs) for patients with advanced heart failure : analysis of the British NHS Bridge to Transplant (BTT) program [PDF]

, 2001
Background: A previous cost-effectiveness analysis showed that bridge to transplant (BTT) with early design left ventricular assist devices (LVADs) for advanced heart failure was more expensive than medical management while appearing less beneficial ...
Aileen Clarke, Ruth Pulikottil-Jacob, Martin Connock, Gaurav Suri, Ngianga-Bakwin Kandala, Hendramoorthy Maheswaran, Nicholas R. Banner, Paul Sutcliffe, Aaronson, Garber, Weinstein, Slaughter, Temple, MacGowan, Clegg, Clegg, Sharples, Sharples, Sharples, Slaughter, Sharples, National Institute for Health and Clinical Excellence, Gohler, Rogers, Personal social services research unit, Briggs, Levy, Schaffer, Strueber, Rose, Stevenson, National Institute for Health and Clinical Excellence, Moreno, Pagani   +33 more
core   +6 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Incremental Cost Estimates for the Patient-Centered Medical Home [PDF]

, 2009
Based on data from thirty-five primary care practices, analyzes the costs associated with the medical home model, in which primary care practices also provide care coordination, patient education, and related services.
Aimee Williams, David Gans, Katie Merrell, Robert A. Berenson, Shari Erickson, Stephen Zuckerman, Terry Hammons, William Underwood   +7 more
core  

In-Hospital Outcomes of Heart Failure Patients with Valvular Heart Disease: Insights from Real-World Claims Data

ClinicoEconomics and Outcomes Research, 2023
Chisato Izumi,1 Rei Matsuyama,2 Kaoru Yamabe,2 Kosuke Iwasaki,3 Tomomi Takeshima,3 Shannon ME Murphy,4 Lida Teng,5 Ataru Igarashi5,6 1Division of Heart Failure, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka ...
Izumi C, Matsuyama R, Yamabe K, Iwasaki K, Takeshima T, Murphy SME, Teng L, Igarashi A   +7 more
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Falling Behind: Americans' Access to Medical Care Deteriorates, 2003-2007 [PDF]

, 2008
Presents survey results on access to medical care for the insured and the uninsured, the healthy and the ill, and for children in wealthy and poor families.
Laurie E. Felland, Peter J. Cunningham
core  

Comorbidities and Factors Determining Medical Expenses and Length of Stay for Admitted COVID-19 Patients in Korea

Risk Management and Healthcare Policy, 2021
Su Yeon Jang,1,* Jeong-Yeon Seon,1,* Seok-Jun Yoon,2 So-Youn Park,3 Seung Heon Lee,4,* In-Hwan Oh1,* 1Department of Preventive Medicine, School of Medicine, Kyung Hee University, Seoul, South Korea; 2Department of Preventive Medicine, Korea University ...
Jang SY, Seon JY, Yoon SJ, Park SY, Lee SH, Oh IH   +5 more
doaj  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Limited Options to Manage Specialty Drug Spending [PDF]

, 2012
Outlines rising trends in costs of and spending on specialty drugs; health plans' efforts to curb specialty drug spending, including patient cost sharing and utilization management; and efforts to integrate medical and pharmaceutical ...
Divya R. Samuel, Ha T. Tu
core