Results 41 to 50 of about 1,613,161 (302)

Applying the False Claims Act to Chemical and Physical Restraint Cases: Is the Government Going Too Far? [PDF]

open access: yes, 2007
On August 6, 2002, Jeanne W. Price, a 79-year-old Alzheimer’s patient at the Central Montgomery Medical Center (CMMC), died while in a restraining device called a Posey vest. The CMMC staff used the restraint to keep Ms. Price from wandering the halls of
Schaadt, Amie E.
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Telemanipulation of an Articulated Robotic Arm using a Commercial Virtual Reality Controller

open access: yesCurrent Directions in Biomedical Engineering, 2020
Access to systems for robot-assisted surgery is limited due to high costs. To enable widespread use, numerous issues have to be addressed to improve and/or simplify their components. Current systems commonly use universal linkage-based input devices, and
Schäfer Max B.   +3 more
doaj   +1 more source

Laser machining apparatus Patent [PDF]

open access: yes, 1971
Laser machining device with dielectric functioning as beam waveguide for mechanical and medical ...
Chioa, R. Y.   +2 more
core   +1 more source

Benefits of and barriers to involving users in medical device technology development and evaluation [PDF]

open access: yes, 2007
Objectives: This study investigated the benefits of, and barriers to user involvement in medical device technology development and evaluation. Methods: A structured review of published literature in peer-reviewed journals. Results: This review revealed
Robinson, I, Shah, SGS
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Powering a Biosensor Using Wearable Thermoelectric Technology [PDF]

open access: yes, 2018
Wearable medical devices such as insulin pumps, glucose monitors, hearing aids, and electrocardiograms provide necessary medical aid and monitoring to millions of users worldwide.
Bals, Anneliese   +5 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Decoding hand and wrist movement intention from chronic stroke survivors with hemiparesis using a user-friendly, wearable EMG-based neural interface

open access: yesJournal of NeuroEngineering and Rehabilitation
Objective Seventy-five percent of stroke survivors, caregivers, and health care professionals (HCP) believe current therapy practices are insufficient, specifically calling out the upper extremity as an area where innovation is needed to develop highly ...
Eric C. Meyers   +7 more
doaj   +1 more source

Application and Prospects of Electrical Impedance Tomography in Perioperative Brain Imaging Monitoring

open access: yesZhongguo yiliao qixie zazhi
Electrical impedance tomography (EIT) represents an emerging medical functional imaging technology, which operates by applying safe-to-human excitation currents through surface-mounted electrodes, measuring boundary voltages between electrodes, and ...
Guofei YAN   +4 more
doaj   +1 more source

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