Results 81 to 90 of about 1,613,161 (302)

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Systematic review and meta-analysis on fully automated digital cognitive behavioral therapy for insomnia

npj Digital Medicine
Insomnia impairs daily functioning and increases health risks. Cognitive behavioral therapy for insomnia (CBT-I) is effective but limited by cost and therapist availability.
Ji Woo Hwang, Ga Eun Lee, Jae Hyun Woo, Sung Min Kim, Ji Yean Kwon   +4 more
doaj   +1 more source

Development of a Lumped Parameter Model of Human Whole Body Circulatory Loop

IEEE Access
The simulation of human cardiovascular dynamics is essential for understanding organ pathology and advancing cardiovascular assistive devices. However, a notable gap remains in defining comprehensive hemodynamic parameters for testing ventricular assist ...
Xun Liu, Chenghuai Mo, Jiaxing Li, Hongyi Yu, Sheng Hu, da Zhu, Puming Zhang, Yonghua Li   +7 more
doaj   +1 more source

CBmeter- a new medical device for early screening of metabolic diseases [PDF]

, 2018
Type 2 diabetes mellitus (T2DM) is a highly prevalent disease worldwide which is asymptomatic in about 44% of patients being critical to search for new ways of early diagnosis.
Brito, Gabriel, Fonseca-Pinto, Rui, Guarino, Maria Pedro, Lages, Marlene, Lopes, Nuno Vieira   +4 more
core  

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Evaluation of blood-tumor barrier permeability and doxorubicin delivery in rat brain tumor models using additional focused ultrasound stimulation

Scientific Reports
Focused ultrasound (FUS) has emerged as a promising technique for temporarily disrupting the blood-brain barrier (BBB) and blood-tumor barrier (BTB) to enhance the delivery of therapeutic agents.
Hyo Jin Choi, Mun Han, Byeongjin Jung, Hyungkyu Huh, Eun-hee Lee, Jong-ryul Choi, Juyoung Park   +6 more
doaj   +1 more source

Peptides as potent antimicrobials tethered to a solid surface: Implications for medical devices [PDF]

, 2008
Medical devices are an integral part of therapeutic management; despite their importance, they carry a significant risk of microbial infection. Bacterial attachment to a medical device is established by a single, multiplying organism, leading to ...
Ahmed El-Ghannam, Dilhari DeAlmeida, Ivan A. Gonzalez, Kazi Islam, Raymond B. Yurko, Ronald C. Montelaro, Simon C. Watkins, Timothy A. Mietzner, XiXi Wong   +8 more
core   +1 more source

Integrating Failure Mode Effect Analysis into the Medical Device Approval Process [PDF]

, 2014
Medical devices that utilize computer software are becoming common place in today’s health care environment. Device failures can have life threatening consequences.
Kurniawati, Vania, Nindel-Edwards, Jim, Steinke, Gerhard   +2 more
core   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Investigation on the Role of Medical Recombinant Human-Derived Collagen Functional Dressings in Wound Healing

Zhongguo yiliao qixie zazhi
ObjectiveTo investigate the biological effect of medical recombinant human-derived collagen functional dressings in wound healing. MethodsMTT assay and RTCA assay were used to detect cell toxicity and proliferation.
Xiaoxiao GAI, Xiaoxia SUN, Wenqian MA, Zhenhua LIN, Xinyuan LI, Chenghu LIU   +5 more
doaj   +1 more source