Results 101 to 110 of about 9,698,373 (354)

Theorising Personal Medical Devices

open access: yes, 2017
This chapter theorises Personal Medical Devices (PMDs) as technologies and as agents in the construction of self and society. PMDs are at the forefront of technological evolution, taking on biological properties. As interactive network devices, they also
Steve Matthewman, Matthewman, Steven
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Thrombogenic and Inflammatory Reactions to Biomaterials in Medical Devices

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Blood-contacting medical devices of different biomaterials are often used to treat various cardiovascular diseases. Thrombus formation is a common cause of failure of cardiovascular devices.
C. Labarrere, A. E. Dabiri, G. Kassab
semanticscholar   +1 more source

THE EU IMPORT REQUIREMENTS FOR MEDICAL DEVICES BY COMPARISON WITH THE USA AND THE GHTF GUIDELINES [PDF]

open access: yes
Medical devices and supply companies are under enormous pressure to fulfill trade requirements dictated by current global markets, especially by the EU, although it is largely recognized that the innovative medical devices and procedures can ...
STRACIUC Oreste   +3 more
core  

Dangerous medical practices related to exposure tо blood and body liquids in medical staff at risk

open access: yes, 2021
Introduction: Health services create conditions for occupational risks related to the health and safety of health workers. The management of safe and healthy working conditions in healthcare is the basis of public healthcare.Aim: The aim of the study is ...
Radoslavova, Biserka; Nadezhda Medical Center, Varna   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

An inclusive approach towards designing medical devices for use in the home environment

open access: yes, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.An emerging trend of the healthcare industry is the huge increase in the number of medical devices being used by lay people at home.
Cifter, Abdusselam Selami
core  

OPENMIND - On-demand production of entirely customised minimally invasive medical devices - H2020

open access: yes, 2023
6062With the development of powerful real-time imaging modalities, the sector of minimally invasive surgery has grown massively in the last decades. The easy and reliable navigation of the medical devices used in these environments is one of the key ...

core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Cortical Plasticity Induced by Pairing Primary Motor Cortex Transcranial Magnetic Stimulation With Subthalamic Nucleus Magneto-Acoustic Coupling Stimulation

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering
Paired cortical and deep stimulation has the potential to induce enhanced cortical plasticity. Ideally, such stimulation should be noninvasive and precisely controlled.
Ruixu Liu   +12 more
doaj   +1 more source

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