Results 11 to 20 of about 668,679 (120)

Review of investigational medical devices' clinical trials and regulations in Africa as a benchmark for new innovations

Frontiers in Medical Technology, 2022
Medical technologies present a huge potential in improving global health playing a key role toward achieving Sustainable Development Goal 3 by 2030.
Brian Matovu, Mercy Takuwa, Charles Norman Mpaata, Fiona Denison, Noah Kiwanuka, Steff Lewis, John Norrie, Sam Ononge, Owen Muhimbise, Sharon Tuck, Maureen Dimitri Etuket, Robert T. Ssekitoleko   +11 more
doaj   +1 more source

Use of National Database of Health Insurance Claims and Specific Health Checkups for examining practical utilization and safety signal of a drug to support regulatory assessment on postmarketing drug safety in Japan

Frontiers in Medicine, 2023
The Pharmaceuticals and Medical Devices Agency (PMDA) has conducted many pharmacoepidemiological studies for postmarketing drug safety assessments based on real-world data from medical information databases.
Haruka Shida, Kazuhiro Kajiyama, Sono Sawada, Chieko Ishiguro, Mikiko Kubo, Ryota Kimura, Mai Hirano, Noriyuki Komiyama, Toyotaka Iguchi, Yukio Oniyama, Yoshiaki Uyama   +10 more
doaj   +1 more source

The assessment of xenogeneic bone immunotoxicity and risk management study

BioMedical Engineering OnLine, 2019
Background Xenogeneic bone has been widely used in a variety of clinical bone-related disease to promote bone healing and restore bone defects. However, the adverse effects of immune system limit its application in the clinic.
Xiaoxia Sun, Chenghu Liu, Yanping Shi, Chunling Li, Likui Sun, Li Hou, Xin Wang   +6 more
doaj   +1 more source

Inhibition of the PI3K but not the MEK/ERK pathway sensitizes human glioma cells to alkylating drugs

Cancer Cell International, 2018
Background Intrinsic chemoresistance of glioblastoma (GBM) is frequently owed to activation of the PI3K and MEK/ERK pathways. These signaling cascades are tightly interconnected however the quantitative contribution of both to intrinsic resistance is ...
Bodo Haas, Veronika Klinger, Christina Keksel, Verena Bonigut, Daniela Kiefer, Julia Caspers, Julia Walther, Maria Wos-Maganga, Sandra Weickhardt, Gabriele Röhn, Marco Timmer, Roland Frötschl, Niels Eckstein   +12 more
doaj   +1 more source

Cardiovascular risk of urate‐lowering drugs: A study using the National Database of Health Insurance Claims and Specific Health Checkups of Japan

Clinical and Translational Science, 2023
In the present study, we aimed to investigate the association between urate‐lowering drugs and cardiovascular events, primarily focusing on the risk of febuxostat and topiroxostat when compared with allopurinol in Japan.
Sono Sawada, Kazuhiro Kajiyama, Haruka Shida, Ryota Kimura, Yuki Nakazato, Toyotaka Iguchi, Yukio Oniyama, Chieko Ishiguro, Yoshiaki Uyama   +8 more
doaj   +1 more source

Causation as a condition for liability of medical employees [PDF]

Zbornik Radova Pravnog Fakulteta u Nišu, 2019
In order to hold a health care worker or a health care institution liable for damage caused to the patient, it is necessary to determine the causation as one of the permanent conditions for establishing liability.
Manić Samir
doaj  

Hallucinations in medical devices

Artificial Intelligence in the Life Sciences
Computer methods in medical devices are frequently imperfect and are known to produce errors in clinical or diagnostic tasks. However, when deep learning and data-based approaches yield output that exhibit errors, the devices are frequently said to ...
Jason Granstedt, Prabhat Kc, Rucha Deshpande, Victor Garcia, Aldo Badano   +4 more
doaj   +1 more source

Strict liability of medical workers for damages by medical devices: Arguments pro et contra [PDF]

Anali Pravnog Fakulteta u Beogradu, 2018
The former Yugoslav law, as well as the law in all former Yugoslav republics, adopts the so-called open system of strict liability, so if the patient suffers damage due to dangerous medical device usage, medical workers, in general, may be held liable ...
Nikolić Đorđe L.
doaj   +1 more source

Quality analysis of manufacturer's incident reports regarding medical devices

Journal of Pharmaceutical Policy and Practice, 2023
Background Medical devices provide a great number of medical treatments and have an important role in patients’ healthcare; however, there are certain risks, sometimes even serious incidents, associated with their usage.
Antonela Simunovic, Krunoslav Kranjcec, Marija Pekas, Siniša Tomic   +3 more
doaj   +1 more source

A STRATEGIC FRAMEWORK FOR START-UP MEDICAL DEVICE MANUFACTURERS IN SOUTH AFRICA

South African Journal of Industrial Engineering, 2019
An exploratory, qualitative study was conducted to establish why local medical device manufacturing firms are not starting up in South Africa. Semi-structured interviews were conducted with local medical device manufacturers to understand the market and ...
Maharaj, Ishan , Sunjka, Bernadette Patricia   +1 more
doaj   +1 more source